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postmenopausal women 71 articles

Statins linked to increased irritability in postmenopausal women

Cholesterol-lowering statin medications may make women more fussy but may help temper aggression in men, according to a new study published in the journal PLOS ONE. Statins, such as the widely prescribed Lipitor, are used to lower cholesterol levels in order to reduce a person’s risk of heart disease, heart attacks and strokes. Previous studies have shown that low cholesterol has been linked to a risk of violent actions and death from violence. There have also been reports of people using statins being more irritable and aggressive. Dr. Beatrice A. Golomb, professor of medicine at the University of California-San Diego ... Read More

Analysis: Statins benefits overrated, side effects underreported

Statin medications, such as the widely prescribed Lipitor, can drive down elevated cholesterol levels, but they have failed to substantially improve users’ chances of having a heart attack or stroke. The drugs also have numerous serious side effects that are pushed under the radar by supporters of statin therapy, according to a study published in the March edition of the medical journal Expert Review of Clinical Pharmacology. Dr. David M. Diamond, a professor of psychology, molecular pharmacology and physiology at the University of South Florida, and Dr. Uffe Ravnskov, an independent health researcher and an expert in cholesterol and cardiovascular ... Read More

Most Medicare recipients not filling statin prescriptions after heart-related hospitalization

The majority of Medicare beneficiaries do not fill prescriptions for high-intensity statin drugs after being hospitalized for complications related to coronary heart disease, a new study has found. Researchers with the Icahn School of Medicine at Mount Sinai in New York City examined the proportion of Medicare recipients filing statin prescriptions after being discharged from the hospital for a cardiac event. They found that only 27 percent of first post-discharge prescription fills among 8,762 Medicare beneficiaries filling a statin prescription after a cardiovascular event were for a high-intensity statin. Cholesterol-lowering statins are prescribed to help prevent heart attacks and strokes ... Read More

Experimental cholesterol lowering drug continues to perform well in clinical trials

An experimental injectable cholesterol lowering drug continues to perform well in clinical trials. The latest studies show the drug can effectively lower “bad” cholesterol even when administered once every four weeks instead of once every two weeks. Alirocumab belongs to a novel class of drugs that lower cholesterol levels by blocking a naturally occurring protein called PCSK9, which inhibits the liver from releasing LDL cholesterol, the so-called “bad” cholesterol. The new class of drugs will offer an alternative to patients with high cholesterol who do not respond well to or cannot tolerate the widely used statin drugs, such as Lipitor. ... Read More

Women more susceptible to medication side effects

Women are more susceptible to medication side effects from certain products than men, according to recent studies. Last year, the Food and Drug Administration (FDA) announced that it was lowering the recommended dosage for women for the sleep aid Ambien (zolpidem) by half because many reported still being under the influence of the drug the next day, causing slower reaction times. It marked the first time ever the FDA showed a gender difference in how men and women experience drug side effects. The reason, the agency and its researchers said, was that the drug lingered in women’s bodies longer than men. The question ... Read More

Statins linked to weight gain, increased blood sugar, type 2 diabetes

Statins were once considered the holy grail of medications, lowering cholesterol levels and promising protection against heart attacks, strokes and premature death. But decades later, with millions of user side effect reports filed away, the ugly truth comes out – statins can make you resist exercise, gain weight, increase your blood sugar levels, and raise your chances of developing type 2 diabetes. Statins, including the widely prescribed Lipitor, are one of the most prescribed drugs in the world. New guidelines offered by the American Heart Association and other organizations are recommending wider use of the drugs, which means even millions ... Read More

Even normal weight, underweight people can get type 2 diabetes

Nine out of 10 people diagnosed with type 2 diabetes are overweight, with a body mass index, or BMI, of 25 to 29.9. About half of the newly diagnosed are obese, with a BMI of 30 or higher, according to a Diabetes UK analysis. Weight gain, unhealthy diets and sedentary lifestyles increase one’s risk of developing the chronic disease. However, more than 10 percent of type 2 diabetics have normal weight and a handful are even underweight, which means no one is immune. Type 2 diabetes is growing in epidemic proportions. People with the condition must follow a strict diet ... Read More

Statins increase diabetes risk, but may protect against diabetes-related blood vessel damage

Cholesterol-lowering statin medications, such as the widely prescribed Lipitor, may protect diabetics against diabetes-related damage to small blood vessels that can cause to blindness and neuropathy, which can lead to amputations, a new study suggests. However, the drugs may cause non-diabetics to develop the disease. Statins are used to lower the risk of heart attacks and strokes in people with elevated cholesterol levels. Statin side effects, which include muscle injury and liver damage, also include increased blood sugar levels, which can increase the risk for type 2 diabetes. It is this adverse event, however, that researchers focused in on for ... Read More

Statin side effects may not be worth the benefits for some people

Kailash Chand admitted he dismissed complaints of muscle pains, weakness, fatigue and memory problems he heard from patients he put on cholesterol-lowering statins. Then his own doctor discovered he had high cholesterol, and put him on statins to lower his risk of heart attacks, strokes and death. It wasn’t long before Chand, too, started experiencing problems. “My regular exercise was curtailed. I was feeling tired and exhausted,” Chand, deputy chairman of the British Medical Association, told Web MD. A stabbing pain in his back sent him to a specialist. When blood tests, X-rays and MRI scans showed no signs of ... Read More

Lipitor side effects lawsuits mount against Pfizer

Lawsuits are mounting against Pfizer Inc., alleging the company withheld information that its cholesterol-lowering statin drug Lipitor could cause women to develop type 2 diabetes. In the past five months, Lipitor side effects lawsuits have jumped from 56 to more than 1,000. With the number of lawsuits growing so quickly, the federal judicial panel consolidated all Lipitor lawsuits in Charleston, S.C. Pfizer fought the decision, claiming that it might cause more people to file lawsuits against the company. Lipitor is the best-selling prescription drug in the world, generating more than $130 billion in sales since it hit the market in 1996. ... Read More