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pre-diabetes 11 articles

FDA panel recommends approving diabetes treatment for obese patients

A Food and Drug Administration (FDA) advisory panel has given a thumbs-up recommendation to Novo Nordisk’s type 2 diabetes drug liraglutide for the treatment of chronic obesity in patients with at least one weight-related health issue, such as hypertension or pre-diabetes. Liraglutide, known commercially as Victoza, would be sold under the label Saxenda for the obesity indication if it is approved by the FDA. The agency is not required to follow the recommendations of its advisory panels, but it usually does. The positive recommendation was based on a clinical trial in which patients were given 3 mg of liraglutide. About ... Read More

Pre-diabetes diagnoses benefit drug companies more than patients

Non-diabetics with higher-than-recommended blood sugar levels and thus at risk for developing type 2 diabetes are considered pre-diabetic, however classifying large numbers of people with pre-diabetes offers more benefit to drug companies than those diagnosed with the condition, researchers argue. In an editorial published in the British Medical Journal, researchers with University College London and the Mayo Clinic in Minnesota said that labeling people as pre-diabetic increases the likelihood that they will be prescribed medication prematurely, which would at best only briefly delay the onset of illness. It would also prematurely expose them to potential side effects from the drugs. John ... Read More

Number of diabetics continues to escalate year after year

The rate of diabetes and pre-diabetes in the United States continues to rise dramatically, so much so that the Centers for Disease Control and Prevention (CDC) warns one in every three Americans will have the condition by 2050. The new National Diabetes Statistics Report estimates that from 2010 to 2012, the number of adults with diabetes jumped from 26 million to nearly 30 million, and that a quarter of those individuals don’t know they have the disease. Uncontrolled diabetes can cause serious complications including heart disease, kidney disease, blindness, and amputations due to neuropathy. Also alarming is that another 86 ... Read More

NIH study to test whether vitamin D can prevent or delay onset of type 2 diabetes

Vitamin D use has increased dramatically in the United States in the past 15 years and has been credited with reducing the risk of developing multiple sclerosis, heart disease, and even type 2 diabetes. But many of the claims have yet to be substantiated through research. That is, until now. The National Institutes of Health (NIH) announced that it would be conducting studies to determine whether vitamin D can prevent or delay the onset of type 2 diabetes in adults at risk for developing the disease. “We need rigorous testing to determine if vitamin D will help prevent diabetes,” said ... Read More

People with healthy but elevated blood sugar levels more likely to have memory problems

People with slightly elevated but not unhealthy levels of sugar in their blood are more likely to perform worse on memory tests than people with lower levels, according to a new study. Previous studies have shown that people with blood sugar disorders such as pre-diabetes and diabetes are more likely to have poor brain function and dementia. A team of researchers led by Agnes Floel, a neurologist at Charite University Medicine in Berlin, set out to see if the same was true for people with slightly higher – but still considered normal – blood sugar levels. The study involved 141 ... Read More

Analyst: diabetes drug sales expected to more than double by 2020

Sales of diabetes drugs should keep growing at about 10 percent a year for the rest of the decade, reaching $65 billion a year by 2020, says Jeffrey Holford, an analyst with Jefferies & Co. At that pace, diabetes drug revenues should more than double from the current $30 billion by the decade’s end. Holford says diabetes drug revenues should rise in relation to the aging population in the West, while in emerging markets, diabetes and obesity are increasing and access to health care is also growing. Other factors considered include higher drug prices, strong patent protection for key drugs, ... Read More

Study shows daily insulin injections do not raise risk for heart attack, stroke, cancer

The safety of diabetes medications has been a concern since the Food and Drug Administration (FDA) issued warnings about cancer and heart attacks associated with the type 2 diabetes drugs Actos and Avandia. For decades, people have wondered if the use of another diabetes medication – insulin – made diabetics more susceptible to cardiovascular disease and cancer. But, a new study offers some peace of mind, indicating long-term, daily injections of insulin do not appear to increase the risk for heart attacks, strokes, or cancer in people with type 2 diabetes or pre-diabetes. The new international study, led by Canadian researchers, ... Read More

Aggressive approach needed to prevent diabetes in pre-diabetics

An earlier and more aggressive approach is needed in people at risk for developing type 2 diabetes in order to reduce the escalating number of people diagnosed with the disease each year, according to a study published in the Lancet. Type 2 diabetes is on the rise worldwide and unhealthy diets and sedentary lifestyles are to blame. People in the early stages of diabetes, known as pre-diabetes, who ignore important warning signs, such as elevated blood sugar, will most likely go on to develop the condition. Once someone develops type 2 diabetes, it is almost impossible to fully recover. However, ... Read More

Diabetics urged to avoid Actos due to cancer risk

People with type 2 diabetes should use the drug Actos (pioglitazone) only if all other options have failed, and people with pre-diabetes should never use it, says Consumer Reports, the well-known consumer watchdog organization. Two recent studies found that the drug increases the risk for bladder cancer, particularly in men and with long-term use. The first study involved 193,000 people 40 or older with type 2 diabetes. The second study involved 1.5 million people. The data prompted the Food and Drug Administration (FDA) to issue a safety warning for all drugs that contain the active ingredient pioglitazone. This includes the brand ... Read More

Deen drops two pant sizes after announcing diabetes diagnosis

Television celebrity chef Paula Deen told People magazine that she has dropped two pant sizes since she admitted to viewers last month that she had type 2 diabetes. Deen was diagnosed with the chronic disease three years ago but opted to keep mum and continue featuring high-fat, sugar-loaded recipes on her Food Network television program. She didn’t choose to go public with her diagnosis until she signed on to be a paid spokesperson for the new diabetes treatment Victoza. Deen has received criticism for not coming clean about her diagnosis sooner while continuing to cook up frightfully fattening fare. Type ... Read More