Tagged Articles

progestin 32 articles

Mirena IUD linked to increased breast cancer risk in premenopausal women

Premenopausal women who use a hormone-releasing intrauterine device, such as the Mirena IUD, are at greater risk of developing breast cancer, according to a study recently published in the journal Obstetrics & Gynecology. There are three IUDs marketed in the United States – the ParaGard, Mirena and Skyla. Only Mirena and Skyla, which are both made by Bayer Healthcare, contain a small amount of the levonorgestrel, a synthetic form of the hormone progestin. IUDs are used to prevent pregnancy, but levonorgestrel-releasing IUDs can reduce heavy bleeding and are often given to women to help treat heavy periods, a condition known ... Read More

NuvaRing makers covered up blood clot risks with contraceptive device

Early one morning in June 2008, Lyndsey Agresta, then 27, called her mother and asked for help. She had an unbearable headache and asked her mother to drive her to the emergency room and look after her 5-year-old son. That was when “everything changed,” her mother, Diane Agresta recalls. Doctors discovered bleeding on her brain caused by a blood clot. It was an unusual diagnosis for a young woman, and doctors suspected her NuvaRing contraceptive device likely contributed to the blood clot. Doctors surgically removed two-thirds of Lyndsey’s right cerebral hemisphere, which left her paralyzed and in need of round-the-clock ... Read More

Combination birth control pills discouraged for older women who smoke

A new black box warning will be added to the safety labels of several brands of estrogen-plus-progestin birth control pills urging women who are older than 35 years of age who smoke not to use the medication because it greatly increases their chances of having a heart attack or stroke. Black box warnings, or boxed warnings, are the strongest warning the Food and Drug Administration (FDA) requires, and signifies that medical studies indicate that using a drug carries a significant risk of serious or even deadly adverse effects. The warnings will be placed on the following oral contraceptives: Modicon (norethindrone/ethinyl ... Read More

Bayer introduces new hormone-releasing IUD Skyla

The Food and Drug Administration (FDA) has approved a new contraceptive device  made by Bayer HealthCare Pharmaceuticals. Skyla, an intrauterine device (IUD) that releases the hormone levonorgestrel, is placed in the uterus to prevent pregnancy for up to three years. Skyla was found to be more than 99 percent effective at preventing pregnancy and is an attractive contraception alternative to the birth control pill, which must be taken daily. The device is a small, flexible plastic T-shaped device containing 13.5 mg of the progestin hormone levonorgestrel. Because Skyla slowly releases levonorgestrel into the uterus, only small amounts of the hormone ... Read More

Study suggests timing of HRT affects dementia risk

How soon after menopause a woman uses hormone replacement therapy (HRT) may determine her risk for developing dementia, a new study published online in the journal Neurology suggests. The numerous studies conducted on the effects of HRT in women have come to different conclusions about whether the menopause treatment lowers or raises a woman’s risk for Alzheimer’s disease and dementia. Observational studies, or those that follow a group over a period of time, show a reduced risk of dementia in women who use HRT, whereas clinical trials, which test the effects of a drug against placebo, show an increased risk. ... Read More

Ortho Evra birth control patch now warns of death, permanent disability from blood clots

Stronger warnings have been placed on packages of the Ortho Evra birth control patch, informing users that studies suggest women who use the patch are at greater risk of developing potentially life-threatening blood clots than women who use some oral contraceptives. Birth control pills with the combined hormones estrogen and progestin carry a risk for blood clots. Ortho Evra is a combined hormone contraceptive, containing the progestin norelgestromin and the estrogen ethinyl estradiol. The patch is a thin, matrix-type transdermal patch that is applied to the skin and gradually releases the active ingredients to stop ovulation in order to prevent ... Read More

Combined birth control pills provide limited PMS pain improvement

Combined birth control pills can help reduce the pain of menstrual cramps, but not much, according to a Swedish longitudinal study. Combined oral contraceptives contain two hormones – estrogen and progestin. They work by stopping ovulation and by making the lining of the uterus thinner. There are several hormone varieties of combined birth control pills. The study wasn’t limited to a particular formulation; however, some birth control pills are also approved by the Food and Drug Administration (FDA) to treat acne, such as OrthoTri-cylclen, and another, Yaz, has been approved to treat the symptoms of PMDD, a more severe form ... Read More

Studies show Yaz, Yasmin cause more blood clots

The U.S. Food and Drug Administration (FDA) and Health Canada have announced they are reviewing studies on the health risks associated with the birth control pills Yaz and Yasmin, as well as their generic equivalents. An early review of studies comparing oral contraceptives with the hormone drospirenone, such as Yaz and Yasmin, with pills containing another type of progestin, show that drospirenone-containing pills increase women’s risk for blood clots. The studies were published in a recent issue of the British Medical Journal. Yaz and Yasmin are made by Bayer, which heavily marketed the pills not only as a contraceptive, but ... Read More

FDA warns of elevated blood clot risk in Yaz birth control pills

Two new studies showing an increased risk in venous thromboembolism (VTE), or blood clots in the lungs, in women who use Yaz birth control pills and oral contraceptives with similar hormone formulations, has resulted in a special drug safety notification from the Food and Drug Administration (FDA). Yaz, made by Bayer, contains the progestin drospirenone. The same hormone is used in Bayer’s Yasmin, Beyaz and Safyral, as well as generics such as Ocella, Gianvi, Loryna, Syeda, and Zarah. The studies referenced by the FDA looked at VTE rates in women using birth control pills containing drospirenone compared with women taking ... Read More

Young women at even greater risk for blood clots with Yaz, Yasmin

Bayer has long denied that its birth control pills, Yaz and Yasmin, put women at greater risk for life threatening blood clots, but a new study published in the British Medical Journal says the “fourth generation” oral contraceptives, which contain the progestin drospirenone, put women at twice the risk for blood clots than those that contain the hormone levonorgestrel. Levonorgestrel is a progestogen that is used in both combination hormone pills and progestogen-only formulations. It is known by the brand names Escapelle, Plan B, Levonelle, NorLevo, Postinor-2, i-pill, Next Choice, and 72-HOURS. It is also the active ingredient in the ... Read More