Tagged Articles

propoxyphene-containing drugs 10 articles

Darvon, Darvocet may have caused more deaths than any other painkiller

Before it was removed from the market late last year, Darvon, Darvocet and other painkillers containing propoxyphene were considered by some professionals as having caused more deaths annually than any other drug. It is listed by the U.S. Drug Enforcement Agency as one of the country’s top ten abused drugs, and was banned in the United Kingdom and Europe for years before the United States followed suit. At the time it was pulled from the U.S., an estimated 20 to 40 million prescriptions were written for the drug every year for the past 50 years. The bottom line – propoxyphene-containing ... Read More

More lawsuits filed over painkiller Darvocet

More lawsuits are being filed against Xanodyne Pharmaceuticals over the newly banned prescription painkiller Darvocet, from plaintiffs who claim they suffered bodily harm after taking the drug. Darvocet, which includes the active ingredient propoxyphene, was pulled from the United States market late last year after new studies showed the drug put users at risk for potentially fatal heart rhythm abnormalities. The latest lawsuit was filed by Deborah M. Rogers, individually and on behalf of others similarly situated, in federal court in New Orleans. The lawsuit accuses Xanodyne Pharmaceuticals of failing to warn users of the risks and side effects associated ... Read More

Public Citizen raised flags about Darvocet, now warns of Alli, Xenical

Consumer watchdog group Public Citizen was the first to raise concerns about the safety of propoxyphene, the active ingredient in the brand-name drugs Darvocet and Darvon. The group petitioned the Food and Drug Administration (FDA) twice since the prescription painkiller was introduced more than 50 years ago. Public Citizen claimed the drug had a sketchy track record for efficacy and that patients were needlessly dying from accidental overdoses while taking the drug. The FDA opted to keep propoxyphene-containing drugs on the market, but did agree to put stronger warnings on the product’s safety label. Still, Public Citizen urged, it was ... Read More

Heart problems linked to popular prescription painkiller

People who have experienced heart problems over the past several years may not be aware that their condition may have been caused by a common prescription painkiller. Propoxyphene, commonly known by the brand names Darvocet and Darvon, was banned in the United States late last year because a new study linked use of the drug to abnormal heart rhythms. The condition can require hospitalizations, and cause heart attacks and death. The drug was approved in the United States more than 50 years ago to treat mild to moderate pain and had become one of the most prescribed painkillers in the country. However, for ... Read More

Rx drug overdose second leading cause of accidental death

For Alexandra Rain, pain is constant. The 53-year-old woman’s spine and legs were crushed in an automobile accident nearly 35 years ago, and she needs strong prescription painkillers just to make it through the day. Yet the drugs meant to improve her quality of life have left her on the verge of overdose on more than one occasion. “You lose track of what you’re taking because a lot of the time I was advised to ‘take as needed,’” Rain told ABC News. On several occasions she inadvertently OD’d and on one occasion stopped breathing altogether. Rain is not alone. A ... Read More

Lawsuits against Darvon/Darvocet climb as more victims come forward

Attorneys are currently investigating cases of life threatening health problems caused by the popular painkillers Darvon and Darvocet. The Food and Drug Administration (FDA) pulled the drugs from the market late last year after studies linked use of the drugs to abnormal heart rhythms that in some cases resulted in sudden death. Darvon, which has the active ingredient propoxyphene, was approved for the treatment of mild to moderate pain in 1957. Shortly afterward propoxyphene was combined with acetaminophen under the brand name Darvocet, and marketed for similar use. When the patent for propoxyphen expired, generic versions of Darvon and Darvocet ... Read More

Propoxyphene causes many serious health problems

The Food and Drug Administration (FDA) recently banned the popular prescription painkiller propoxyphene, which includes brands such as Darvon and Darvocet, after studies showed the central nervous system depressant increased users’ risk of life-threatening heart rhythm abnormalities. Abnormal heart rhythms are different from heart attacks, where blood flow to part of the heart may be slowed or stopped. These abnormalities may cause cardiac arrest, which is sometimes called sudden cardiac death. During such an event, the heart stops beating and the victim may die within minutes. Other problems associated with abnormal heart rhythms include arrhythmia, which is any abnormal heart ... Read More

Doctor warns muscle relaxer Soma may be as dangerous as banned Darvocet

Why did it take so long for the Food and Drug Administration (FDA) to pull Darvocet from the market? Especially when, on several occasions, FDA advisory committees recommended to the FDA that propoxyphene-containing drugs, like Darvocet or Darvon, should be removed from the market because of safety and dependency concerns? “It perplexed a number of us for many years that individuals were prescribed propoxyphene-containing products when these drugs didn’t appear to provide any greater pain relief than more simple approaches,” says Dr. Charles Argoff, Professor of Neurology at Albany Medical College and Director of the Comprehensive Pain Center at Albany ... Read More

A closer look at the study that lead to the banning of Darvon, Darvocet

Late last year the Food and Drug Administration (FDA) banned the drugs Darvon and Darvocet, also known by the generic propoxyphene, from the U.S. market because new data showed that people who used the drug were at an increased risk for serious abnormal heart rhythms. Here’s a closer look at that data and the problems associated with propoxyphene-containing drugs: The new data came from a 2007 Multiple Ascending Dose (MAD) Study Review which was designed to determine an appropriate dose that could be used in a definitive cardiac study. The drug had just received a black box warning because of ... Read More

Critics: US, Canada took too long to pull Darvon, Darvocet from market

The painkiller propoxyphene, known by the brand names Darvon and Darvocet, has been outlawed by several countries; however, critics are asking why it took so long for the drug to be banned, especially in the United States and Canada. Propoxyphene is a prescription treatment for mild to moderate pain. It has been on the market in the United States for more than 50 years and has become one of the country’s most prescribed painkillers. But concerns about the drug’s safety surfaced as early as 1978, when the American watchdog group Public Citizen petitioned the Food and Drug Administration (FDA) to ... Read More