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prostate cancer 49 articles

Study investigates prostate cancer risk with testosterone treatments

The increased use of testosterone replacement therapy has resulted in numerous studies looking into the safety of testosterone supplementation. Recent studies have brought to light concerning cardiovascular risks. For example, one study has found that men who used testosterone therapy were 30 percent more likely to have a heart attack, stroke or die after three years of use. Another study found that men had a significant increased risk of heart attack and stroke in the first 90 days of use. A recent study has looked at whether testosterone treatment can increase prostate cancer risk. The reasoning is that standard therapy ... Read More

Women should not be treated with testosterone therapy, Endocrine Society advises

Low testosterone is not a valid diagnosis in healthy women, and most women with low amounts of the hormone should not use testosterone-replacement drugs, the Endocrine Society said in a new guideline. “Although limited research suggests testosterone therapy in menopausal women may be linked to improved sexual function, there are too many unanswered questions to justify prescribing testosterone therapy to otherwise healthy women,” guideline task force chair Dr. Margaret Wierman, of the University of Colorado, said in news release. Dr. Wierman said that in a review of past studies, women who had low testosterone levels did not exhibit any signs ... Read More

FDA panel recommends severely limiting testosterone drug prescriptions

A U.S. Food and Drug Administration (FDA) advisory panel voted 20-1 Wednesday to impose strict new limitations on testosterone-replacement drugs, recommending changes to labeling that would limit FDA-approved prescription indications to men who have abnormally low testosterone levels due to injury or disease, but not aging. The changes, triggered by conflicting studies and a lack of evidence showing the efficacy of testosterone drugs for treating common age-related issues, would exclude millions of American men who currently use the drugs as antidotes for low libido, muscle loss, and lack of energy. The panel’s recommendations, which the FDA usually accepts, could also ... Read More

FDA to reassess appropriateness, usefulness of testosterone replacement drugs

The U.S. Food and Drug Administration (FDA) will hold an advisory panel meeting Sept. 17 on the safety and usefulness of testosterone replacement drugs, which a number of pharmaceutical manufacturers are promoting and selling aggressively to men who may be stricken with low testosterone levels, or “Low T.” FDA officials added briefing documents to the agency website earlier this month, acknowledging that while testosterone levels commonly drop in men as they age, studies indicate that lower levels of the hormone do not necessarily lead to serious health problems, such as testicular and pituitary disease. Still, as the agency notes, testosterone ... Read More

Low dose aspirin therapy may help prevent pancreatic cancer

A low, daily dose of aspirin has been praised for its cardiovascular benefits, but new research shows that the therapy may also ward off pancreatic cancer, one of the deadliest forms of the disease. The study, conducted by researchers at the Yale School of Public Health, claims daily low-dose aspirin therapy can lower pancreatic cancer risk by up to 48 percent. Low-dose aspirn therapy has already been credited for reducing risk of ovarian, colorectal, stomach, esophageal, prostate, breast, lung, and skin cancers. Researchers studied information on aspirin use and medical histories for 362 people with pancreatic cancer and 690 people ... Read More

FDA warns that chemotherapy drug may cause patients to feel drunk

The intravenous chemotherapy drug docetaxel contains ethanol, also known as alcohol, which can cause patients to feel intoxicated, or drunk, during and after treatment, the Food and Drug Administration (FDA) warned in a safety communication. The agency is ordering all docetaxel drug products to add a warning to their safety labels regarding this possible side effect. Docetaxel is a prescription chemotherapy drug used to treat various types of cancer including breast, prostate, stomach, head and neck, and non-small-cell lung cancers. It is known by the brand names Taxotere and Docefrez. Known as a taxane, the drug works by interfering with microtubules, ... Read More

Testosterone drugs may seriously harm some patients, doctor warns

National Public Radio (NPR) recently called testosterone replacement drugs “the biggest men’s health craze since Viagra,” but some doctors warn that the supplements could be anything but healthy for some men. The Louisiana State University (LSU) Health Sciences Center in New Orleans recently reported that resident urologist Harold Fuselier warns that testosterone-replacement drugs, which are now widely available in topical gels, creams, and patches, could have serious, even deadly, side effects. It’s an especially important warning to consider, given the proliferation of television, web, and print advertisements touting the advantages of drugs that artificially boost low testosterone levels, often referred ... Read More

FDA sued for failure to publish approval of generic testosterone drug

Multinational generic drug manufacturer Perrigo Israel Pharmaceuticals sued the U.S. Food and Drug Administration (FDA) last Friday in a Washington D.C. federal court after the agency failed to take the appropriate measures that would allow sales of Perrigo’s generic testosterone gel product, even though it had received FDA approval. Ireland-based Perrigo, the largest manufacturer of private label over-the-counter prescription drugs in the United States, said that the FDA failed to update its “Orange Book” listing Approved Drug Products with Therapeutic Equivalence Evaluations. As a result, Perrigo’s testosterone-replacement gel, a generic equivalent of AbbVie’s AndroGel, is not included in the FDA’s therapeutic equivalents (TE) – ... Read More

FDA approves Endo’s new Aveed testosterone injections

U.S. drug regulators gave Irish drugmaker Endo Pharmaceuticals the green light to manufacture and market its long-lasting testosterone injection Aveed in the United States, making it the latest addition to a growing list of testosterone-replacement therapies drug companies are aggressively marketing to men in the U.S. and other countries. Endo Pharmaceuticals said the U.S. Food and Drug Administration (FDA) approved Aveed to treat men with hypogonadism, commonly referred to as “low testosterone” or “low T,” a condition in which the body produces lower than normal levels of the hormone. Men with abnormally low testosterone levels often experience declines in muscle, ... Read More

FDA reassessing testosterone drug safety

The U.S. Food and Drug Administration (FDA) said it plans to review the safety of testosterone replacement drugs after two separate studies indicated a higher risk of adverse cardiac events in men who used the products, including one report that linked the drugs to a doubled risk of heart attack. The agency said it is issuing the alert as it continues to “evaluate the information from these studies and other available data” that point to a significantly higher risk of “stroke, heart attack, and death in men taking FDA-approved testosterone products,” but advised that patients should not stop taking testosterone-enhancing ... Read More