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San Diego 119 articles

San Diego Grapples With Major Hepatitis A Outbreak

Facing an epidemic of homelessness on its streets, the City of San Diego now has a new related problem: a rapidly growing outbreak of Hepatitis A. San Diego County health officials declared a public health emergency in the city as the rate of Hepatitis A infection continues to surge. So far the outbreak has sickened about 400 people and killed at least 15. These numbers are likely larger however because they only reflect the illnesses that have been reported and confirmed. The health officials painted a picture of a downtown San Diego that is akin to an undeveloped country. A ... Read More

Some doctors have stopped prescribing Invokana

New warnings regarding an increased risk of lower limb amputations with diabetes drugs containing canagliflozin have prompted some California doctors to transition patients off the medication, especially if they have key risk factors such as prior amputations. It is a “process that has been underway since the FDA warnings came out,” John Chomsky, a spokesman for Sharp HealthCare system in San Diego, California, told KPBS. Two large studies involving patients taking type 2 diabetes medications containing canagliflozin, which includes the brand-name drugs Invokana, Invokamet and Invokamet XR, showed that the medications doubled the risk of lower limb amputation compared to ... Read More

FDA cracks down on stem cell treatment center

U.S. Marshals, acting on behalf of the Food and Drug Administration (FDA), seized five vials of a commercially unavailable smallpox vaccine from StemImmune Inc., in San Diego, California, in order to prevent the company from using it as a potentially dangerous and unproven treatment for patients at the California Stem Cell Treatment Centers in Rancho Mirage and Beverly Hills, California. The vaccine, Vaccinia Virus Vaccine (Live), is reserved only for people at high risk of smallpox, like some members of the military. Since the vaccine is not commercially available, the FDA said has serious concerns about how StemImmune obtained the ... Read More

Study: Hookah Smoke Linked to Cancer

A recent ongoing study has convinced researchers that a chemical in hookah smoke, both firsthand and secondhand, is linked to cancer, and has been found to contain benzene, according to KBPS.org. A San Diego State University (SDSU) study, funded by the American Cancer Society, has found evidence that burning hookah tobacco creates a chemical that researchers believe causes lung cancer and heart disease. Benzene, which is a known cause of leukemia, was also found in the byproduct. During the study, 3-HPMA (a metabolite of acrolein) was detected in the urine samples of 105 hookah smokers and 103 non-smokers who were exposed to ... Read More

New ADHD medication may improve morning symptoms

Getting kids with attention deficit hyperactivity disorder, or ADHD, ready for school in the morning can be frustrating, to say the least. Kids generally don’t settle down until their morning meds have taken effect. But results from a phase III trial show that an experimental drug known simply as HLD200 significantly improves early morning functioning impairment in children with ADHD. A post-hoc analysis of a secondary outcome in the data was reported during a poster session at the American Psychiatric Association meeting in San Diego, California. The experimental drug is manufactured by Ironshore Pharmaceuticals. Researchers used a “Before School Functioning ... Read More

Tech Firm Shares Commercial Distracted Driving Insight

Distracted driving is now a deadly epidemic in the U.S. Preliminary data from the National Safety Council shows that that 40,200 people died in motor vehicle crashes in 2016 –  a 6 percent rise over 2015 totals and a staggering 14 percent increase in traffic deaths since 2014. A two-year jump like this has not been seen in 50 years. Distracted driving is also incredibly expensive. The estimated cost of motor-vehicle deaths, injuries, and property damage last year was $432.5 billion – a 12 percent increase from 2015. Distraction makes every individual an inferior driver. But one technology and analytics ... Read More

Judge Rules Whistleblowers Can Provide SEC with Confidential Documents To Substantiate Fraud Claims

A San Diego federal judge’s Feb. 14 ruling in a whistleblower dispute involving Bank of Internet (BofI) and a former employee who provided classified information to federal regulators about potential securities violations enhances protections for certain whistleblowers who report fraud. According to Courthouse News Service, U.S. District Judge Cynthia Bashant denied most of BofI’s motions for a summary judgement of whistleblower protections from Charles Matthew Erhart, who was formerly employed as BofI’s internal auditor. Mr. Erhart started working for San Diego-based BofI in September 2013. He reported the bank to the Securities and Exchange Commission (SEC) upon discovering it worked ... Read More

J&J remains mum about results of Invokana study data

Results from the CANVAS and CANVAS-R study investigating cardiovascular risks with the blockbuster type 2 diabetes drug Invokana are expected later this year. Invokana manufacturer Johnson & Johnson (J&J) and its subsidiary Janssen Pharmaceuticals are hoping for label-changing results like that of rival Jardiance, which showed the drug reduced the risk of cardiovascular death in diabetics with heart disease. But some analysts are skeptical. “While pure speculation on our part, it’s possible that J&J has seen more of the CANVAS/CANVAS-R data since the Q3 call and feels less confident in the outlook,” Wells Fargo Securities noted following the drug company’s ... Read More

Study of E-Cigarettes Provides insight to Improve Safety

In a recent study of e-cigarettes, two types of devices were examined: e-cigarettes with one heating coil, and the more expensive two-heating-coil varieties. Researchers examined the emissions from both types of e-cigarettes, using three kinds of juices and using varying battery voltages. The emissions were found to contain diacetyl, formaldehyde and acrolein, and the higher the e-cigarette voltage, the more dangerous chemicals it produced. Prue Talbot, a professor of cell biology and director of the UC Riverside Stem Cell Center, said of the study, “This is an important area of electronic cigarette research and this paper makes new and interesting observations on ... Read More

Truck Plummets Off San Diego Bridge, Killing Four Festival Goers Below

California law enforcement authorities are investigating the crash of a GMC pickup truck that jumped the guardrails on a San Diego bridge and plunged into a festival tent set up in the park below, killing four people and injuring several others. The California Highway Patrol said that 25-year-old Richard Anthony Sepolio, a member of the U.S. Navy, lost control of the vehicle Saturday afternoon as he was driving onto the San Diego-Coronado Bridge westbound from I-5. The truck hopped the guardrail and plunged about 60 feet to Chicano Park below. Mr. Sepolio, who is stationed at the naval base on ... Read More