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selective serotonin reuptake inhibitors 83 articles

Judge refuses to dismiss Prozac birth defects lawsuit

A lawsuit filed by a woman who claims taking Eli Lilly & Co.’s antidepressant Prozac during pregnancy caused her child to be born with a heart defect will move forward after an Alabama federal court refused the drug company’s motion to dismiss the case. U.S. District Judge Keith Watkins found that the plaintiff, Dana Fields, had a genuine dispute against Eli Lilly, and that she could show factual causation that her doctor would not have prescribed the drug to her had he known the risks, even though the doctor is now deceased. Fields claims that in 1996 she took Prozac ... Read More

First federal Zoloft birth defects trial scheduled for January 2016

Five cases in an ongoing federal multidistrict litigation (MDL) alleging Pfizer’s antidepressant Zoloft caused heart defects in children born to women who took the drugs during pregnancy have been selected to go to trial, with the first scheduled to begin in January 2016. The first trial is that of plaintiff Deidra Long, who filed her lawsuit in Pennsylvania state court in May 2012. She claims that her son, Hudson Long, was born in January 2008 with congenital birth defects as a result of exposure to Zoloft while in utero. Since his birth, the boy has suffered serious birth defects including ... Read More

Experts worry about skyrocketing prescriptions for antidepressants

The number of prescriptions for antidepressants has reached a record high in the United Kingdom, and experts fear that some people may be unnecessarily exposed to antidepressant side effects. The Health and Social Care Information Centre released the new figures on prescription drugs, which showed antidepressant use had risen by one-third in just a year, and that about four million Britons are taking the drugs each year – twice as many compared to 10 years ago. Representatives from mental health agencies say they worry that people suffering from depression are prescribed drugs as a first-line defense because other forms of ... Read More

New meta-analysis raises serious questions about SSRI use during pregnancy

There is not enough research to provide a clear guidance on the risks or benefits of antidepressant use during pregnancy, however there are serious concerns regarding the drugs’ affects on newborns that should be addressed, a new meta-analysis has found. The analysis on antidepressant use during and after pregnancy was conducted by U.S. Department of Health and Human Services’ Agency for Healthcare Research and Quality. The study focused on a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand names Zoloft, Prozac, Lexapro, Celexa, and Paxil. Researchers reported finding evidence that SSRI use during ... Read More

Long-term use of antipsychotic Risperdal in children linked to reduced bone mass

Long-term use of the antipsychotic drug Risperdal in children can reduce bone mass and prevent bone growth, according to a new study presented at the American Society of Clinical Psychopharmacology’s annual meeting. Similar results were found in children treated long-term with antidepressants known as selective serotonin reuptake inhibitors, or SSRIs. Risperdal, also known by the generic risperidone, is used to treat symptoms of schizophrenia, bipolar disorder, and irritability with autism. In 2007, the Food and Drug Administration (FDA) approved the medication for use in children and adolescents with those disorders, though the drug’s maker Janssen Pharmaceuticals had illegally marketed the medication to ... Read More

Celexa, Lexapro birth defects lawsuits returned to state court

Fifteen lawsuits over birth defects in children born to women who took the antidepressants Celexa or Lexapro while pregnant were remanded to state court, a federal judge in Camden, N.J., ruled. Attorneys for the drugs’ maker Forest Laboratories unsuccessfully argued that federal jurisdiction was proper because there were questions about the Food and Drug Administration’s (FDA) labeling of the drugs. Defendants’ claims that Forest Research Institute was fraudulently joined as a defendant were rejected as well. The 15 lawsuits are among 20 that were filed in state courts in New Jersey and removed to federal court by the drug companies. ... Read More

New study suggests SSRI use during pregnancy increases risk of autism spectrum disorders in children

Women using antidepressants known as SSRIs (selective serotonin reuptake inhibitors) during pregnancy may be at higher risk of having children with autism spectrum disorders, according to a new study published in the Journal of Autism and Developmental Disorders. Several studies have raised red flags with the use of SSRIs during pregnancy. SSRIs, which include the brand names Zoloft, Paxil, Lexapro, Celexa and Prozac, have been linked to birth defects such as persistent pulmonary hypertension, heart defects, neural tube defects and malformations. Studies have also suggested that children exposed to SSRIs in utero are more likely to have behavioral problems and ... Read More

Study: Children exposed to SSRIs in utero at greater risk for obesity, type 2 diabetes

Babies born to women who took antidepressants while pregnant are more likely to become obese and develop type 2 diabetes, according to a new study. Obesity and type 2 diabetes in children is already on the rise in the United States and is generally blamed on poor diets and reduced physical activity. However, researchers with McMaster University say that maternal antidepressant use may also be a contributing factor in the pediatric obesity and diabetes epidemic. The study focused on a commonly prescribed type of antidepressant known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand names Prozac, Lexapro, ... Read More

SSRI use in third trimester linked to persistent pulmonary hypertension (PPHN) in newborns

Babies born to women who used SSRI antidepressants during the third trimester of their pregnancies were at an increased risk of giving birth to a baby with persistent pulmonary hypertension in the newborn, or PPHN, according to new research. The study, conducted by researchers with the Sunnybrook Health Sciences Center in Toronto, Canada and the University of Toronto, involved data from seven meta-analyses. Researchers looked at maternal use of SSRIs, or selective serotonin reuptake inhibitors, during different trimesters of pregnancy and the incidence of PPHN. The greatest risk of PPHN was found to be in the third trimester. SSRIs include ... Read More

North Carolina woman says prescription drug-induced psychosis led husband to kill daughters

The moment Kim Crespi of Charlotte, N.C., heard that her husband David had stabbed their 5-year-old twin daughters to death, she knew that the real culprit behind the horrific act wasn’t her spouse but a cocktail of prescription drugs, including Selective Serotonin Reuptake Inhibitors, or SSRIs – a form of antidepressants. According to Charlotte’s WBTV, David Crespi, a Charlotte-area banker, called 911 on the morning of Jan. 20, 2006 to report that he had just killed his own daughters. Mr. Crespi was arrested and ultimately took a plea bargain to avoid the death penalty. He is now serving two life ... Read More