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selective serotonin reuptake inhibitors 83 articles

New study shows increased risk of autism in children exposed to SSRIs in utero

Children exposed to antidepressants in their mother’s womb are more likely to develop autism than children who were not exposed to the drugs, a new study suggests. The study identified the risk with both selective serotonin reuptake inhibitors (SSRIs) and nonselective monoamine reuptake inhibitors, or tricyclic antidepressants. This is the second study in two years to associate antidepressant use during pregnancy with an increased risk of autism in offspring. SSRIs are among the most commonly prescribed drugs in the United States, and include brand names such as Zoloft, Paxil, Celexa, Lexapro and Prozac. All SSRIs but Paxil are listed as ... Read More

SSRI use during fertility treatments shows little benefit to mother or fetus

Depressed women taking selective serotonin reuptake inhibitors (SSRIs) who are also undergoing infertility treatment may be more likely not to conceive, to suffer complications with pregnancy, and to have a baby with birth defects, a new meta-analysis shows. Women undergoing infertility treatments often battle depression. A study published in Medical News Today investigated depressed women undergoing infertility treatment and the risks to their fetuses while taking SSRIs. The new meta-analysis took a different approach than past studies, investigating the safety and efficacy of infertile women being treated with SSRIs. Researchers culled through studies and found that SSRI is associated with lowered ... Read More

Newborn’s long list of birth defects blamed on antidepressant Zoloft

Use of the antidepressant Zoloft during pregnancy is considered the primary cause of a long list of serious birth defects in a newborn. The case was reported last year to the Food and Drug Administration (FDA) Adverse Event Reporting Program, and gives a glimpse of the serious effects drugs like Zoloft can have on developing fetuses. The case involved a male baby born weighing about 4 pounds. The congenital defects listed include heart defects such as aortic valve incompetence, atrial septal defect (hole in the heart), cardiomegaly (enlargement of the heart), and mitral valve incompetence and prolapse. The newborn also ... Read More

Pregnant women should be especially careful with over-the-counter, prescription medications

Pregnant women should be extra careful when taking medicines because they may be unsafe for the mother or the child, the Food and Drug Administration (FDA) cautions. The agency issued a reminder to consumers that the risks and benefits of medicines should be carefully weighed in general, but especially in women who are expecting. Pregnancy causes changes in the body, including how medicines are processed. In some cases, dosage may need to be adjusted. Even everyday medicines, including over-the-counter pain relievers, can be unhealthy for both mother and baby. Some medications, including antidepressants known as selective serotonin reuptake inhibitors (SSRIs), have been linked ... Read More

SSRIs linked to increased risk of bleeding events, transfusions after surgery

People who use antidepressants known as selective serotonin reuptake inhibitors (SSRI) and undergo surgery are more likely to have bleeding events, need transfusions, suffer from irregular heart functions, stay in the hospital longer, and die shortly after surgery than people not on antidepressants who had surgery, according to a new study. SSRIs are the most commonly prescribed antidepressants on the market today and include brand names such as Prozac (fluoxetine), Zoloft (sertraline), and Paxil (paroxetine). Numerous studies have shown the dangers of SSRIs on developing fetuses when taken by pregnant women, and on suicide risks when taken by adolescents. The ... Read More

SSRIs do not hinder growth in infants during first year of life, but may cause other problems

A new, small study suggests that antidepressant use during pregnancy may not hinder an infant’s growth its first year of life, however the drugs have been associated with an increased risk of birth defects, premature birth, learning difficulties and even autism. Commonly used antidepressants, known as selective serotonin reuptake inhibitors, or SSRIs, have been the center of much debate when it comes to use by pregnant women. Numerous studies have been conducted to determine the risk to the fetus and the mother. Other studies have looked at the cognitive effects on babies who were exposed to SSRIs before they were ... Read More

SSRIs may not increase stillbirth, infant death, but still carry birth defect risk

The most widely prescribed class of antidepressants, if taken during pregnancy, do not increase the risk of stillbirth or newborn death, a new study suggests. However, several studies have shown that the drugs can cause birth defects, premature birth, and other problems. The lastest study was published in the Journal of the American Medical Association (JAMA) and involved data from prescription registries, patient registries, and birth registries from Denmark, Finland, Iceland, Norway, and Sweden. Data from more than 1.6 million women included about 30,000 pregnant women who had filled a prescription for antidepressants known as selective serotonin reuptake inhibitors, or ... Read More

First SSRI Prozac celebrates 25th birthday this month

This month marks the 25th anniversary of the antidepressant Prozac (fluoxetine). The drug, the first in a class known as selective serotonin reuptake inhibitors (SSRIs) was launched in January 1988. Since then the drug has enjoyed increasing sales. Prozac was prescribed 3.9 million times in 2011 – a 9.2 percent increase from 2010 sales. Prozac, which is now also available in generic versions, is approved by the Food and Drug Administration (FDA) for the treatment of adult and pediatric major depression, adult and pediatric obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder (PMDD). It is also used to ... Read More

SSRIs increase risk of birth defects but not stillbirth or infant death

Taking antidepressants during pregnancy does not increase the chances that the baby will die in utero or shortly after birth, a new study suggests. However, using the medication while pregnant does increase the likelihood that babies will be born with birth defects. The study is based on a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand-name drugs Zoloft, Paxil, Lexapro and Prozac. Researchers studied 1.6 million women who delivered singletons in Nordic countries from 1996 to 2007. Before accounting for risks that can potentially lead to stillbirth or infant death, researchers noticed a ... Read More

Canadian judge certifies class action lawsuit against Paxil

It was devastating for Faith Gibson of British Columbia to learn that her daughter Meah Bartram was born with a hole in her heart. But it was even more crushing for Gibson to learn two weeks later that her daughter’s birth defect could have been prevented. Two weeks after she delivered Meah, drug maker GlaxoSmithKline (GSK) warned doctors that taking the antidepressant Paxil during pregnancy could increase the risk of cardiovascular defects. Faith used Paxil during her pregnancy and based on information available to her at the time, she believed the drug to be safe for her unborn child. When ... Read More