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side effects 624 articles

Risks may out weigh benefits of statins in elderly


Seniors are nearly four times more likely to be prescribed cholesterol-lowering statins than they were in 1999, and in many cases the drugs are being prescribed to the elderly who have no signs of heart disease, exposing them to potentially serious statin side effects. Statins are among the most prescribed drugs in the world. They are designed to drive down high cholesterol levels to help prevent heart attacks, strokes and cardiovascular-related deaths. New guidelines have dramatically expanded by millions the number of patient who are now eligible to take the drugs. The guidelines offer a “risk calculator” to figure a ... Read More

FDA warns of serious side effects with wrinkle fillers


Soft tissue fillers, also known as dermal fillers, facial implants or wrinkle fillers, injected into skin on the face to smooth wrinkles can cause rare but serious side effects if unintentionally injected into blood vessels in the face, the Food and Drug Administration (FDA) warns. Unintentional injection can block blood vessels and restrict blood supply to tissues which can result in embolization, meaning that the filler material has traveled to other parts of the body. Side effects include vision impairment, blindness, stroke, damage and/or death to the skin (necrosis) and underlying facial structures. While unintended injections into blood vessels may ... Read More

Adverse events linked to misuse of IV training solutions

By LeoCarbajal (Own work) [CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons

Numerous patients have fallen ill and one died after receiving infusions of saline products intended for training purposes and not for human use, the Centers for Disease Control and Prevention (CDC) reported. The products involve Wallcur’s simulated intravenous (IV) saline solutions, which were inadvertently distributed to medical clinics, surgical centers and urgent care facilities in numerous states. More than 40 patients were injected with the IV training solutions, and many experienced adverse events including fever, chills, tremors and headaches. Some patients were hospitalized, and one death has been associated with use of the product though the CDC says it is ... Read More

Book links Lipitor to memory problems, dementia


Cholesterol-lowering statin drugs, such as the widely prescribed Lipitor, may gradually degrade the brain by depriving it of cholesterol, causing memory problems, dementia and other cognitive problems, according to the book Lipitor: Thief of Memory. The book, written by Dr.Duanne Graveline, M.D., chronicles the former astronaut and aerospace medical research scientist’s own horrific experience with statins and how he says the drugs caused him to suffer two transient global amnesia events and chronic neuropathy. Graveline’s theory is also explained by his good friend Dr. David Brownstein, who wrote in a blog about how statins work by poisoning an enzyme known ... Read More

FDA to push drugmakers to provide latest drug safety information electronically


Pharmaceutical companies must provide health care providers with the latest available drug safety information via real-time electronic updates, according to a new rule proposed by the Food and Drug Administration (FDA). “This would ensure that the most up-to-date version of the prescribing information is available to health care professionals and the public,” the rule states. The new guidelines require drug makers to include a link on their drugs’ safety labels and outside packaging of the products that connects directly to a publicly accessible online repository with the drug’s most current instructions, including dosage recommendations, adverse events, and contraindications or drug interactions. The new ... Read More

Bayer faces mounting lawsuits over Mirena IUD side effects

mirena IUD

K. had only recently gotten the Mirena IUD following the birth of her son. The contraceptive works for up to five years, but K. asked her doctor to remove it. She was becoming increasingly convinced that her Mirena IUD had caused her weight gain, fatigue, moodiness, and her hair to fall out in clumps. However, when her doctor tried to remove the device, it was nowhere to be found. She had to undergo surgery, where her doctors discovered the device had perforated her uterus and migrated into her abdomen, lodging in her omentum, the tissue that protects and connects the ... Read More

Researchers warn energy drinks are dangerous to children


Energy drinks such as Red Bull, Monster and 5-Hour Energy are not safe for children because kids 6 years old and younger have suffered seizures and heart problems after drinking the highly caffeinated drinks, a new study reveals. Researchers also warn that the drinks should be avoided by people with heart conditions because the effects could be dangerous. Researchers with Wayne State University in Detroit reviewed 5,156 calls to U.S. poison control centers from October 2010 to September 2013, focusing on ones involving energy drinks. The most common cause for the calls was because children accidentally drank an energy drink. ... Read More

UAB researchers to test hypertension drug as a cure for type 1 diabetes


Researchers with the University of Alabama at Birmingham (UAB) will begin testing whether a drug used to treat high blood pressure could be effective in the treatment of type 1 diabetes. Two years ago, researchers tested the drug verapamil, known by the brand names Calan, Verelan and Covera-HS, on laboratory mice and found that it could lower blood sugar levels but in some cases could even reverse the disease. Verapamil is a calcium channel blocker indicated for the treatment of hypertension, severe chest pain and arrhythmia. It is the only drug on the market that works to keep the pancreas’ ... Read More

Researchers: Viagra could be tested as heart disease treatment


The world’s top selling erectile dysfunction drug Viagra could become a new treatment for heart disease, which could increase the number of users as well as expose more people to potentially dangerous side effects. When Viagra was in development 25 years ago, it was not intended to be a treatment for erectile dysfunction. It was being studied as a cardiovascular drug. Unfortunately, several adverse events were reported during clinical trials including the unique side effect of an erection after use. Disappointed with the cardiovascular results Viagra produced, researchers didn’t give up. Instead, they decided to test the drug as a ... Read More

Off-label prescribing of antipsychotic drug raises concerns about side effects


Off-label prescribing of an antipsychotic drug in Canada is raising concerns about serious and life-threatening side effects. Seroquel is only approved in Canada to treat bipolar disorder and schizophrenia. In the United States, however, it is also used as an add-on treatment to an antidepressant for patients with major depressive disorder. According to IMS Health Canada, a company that tracks the health care industry, the number of prescriptions for Seroquel in Canada has risen from 4.1 million in 2008 to 7.4 million in 2013. However, the prescriptions for the drug are vastly disproportionate to the number of Canadians suffering from ... Read More