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side effects 618 articles

Researchers warn energy drinks are dangerous to children

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Energy drinks such as Red Bull, Monster and 5-Hour Energy are not safe for children because kids 6 years old and younger have suffered seizures and heart problems after drinking the highly caffeinated drinks, a new study reveals. Researchers also warn that the drinks should be avoided by people with heart conditions because the effects could be dangerous. Researchers with Wayne State University in Detroit reviewed 5,156 calls to U.S. poison control centers from October 2010 to September 2013, focusing on ones involving energy drinks. The most common cause for the calls was because children accidentally drank an energy drink. ... Read More

UAB researchers to test hypertension drug as a cure for type 1 diabetes

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Researchers with the University of Alabama at Birmingham (UAB) will begin testing whether a drug used to treat high blood pressure could be effective in the treatment of type 1 diabetes. Two years ago, researchers tested the drug verapamil, known by the brand names Calan, Verelan and Covera-HS, on laboratory mice and found that it could lower blood sugar levels but in some cases could even reverse the disease. Verapamil is a calcium channel blocker indicated for the treatment of hypertension, severe chest pain and arrhythmia. It is the only drug on the market that works to keep the pancreas’ ... Read More

Researchers: Viagra could be tested as heart disease treatment

viagra

The world’s top selling erectile dysfunction drug Viagra could become a new treatment for heart disease, which could increase the number of users as well as expose more people to potentially dangerous side effects. When Viagra was in development 25 years ago, it was not intended to be a treatment for erectile dysfunction. It was being studied as a cardiovascular drug. Unfortunately, several adverse events were reported during clinical trials including the unique side effect of an erection after use. Disappointed with the cardiovascular results Viagra produced, researchers didn’t give up. Instead, they decided to test the drug as a ... Read More

Off-label prescribing of antipsychotic drug raises concerns about side effects

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Off-label prescribing of an antipsychotic drug in Canada is raising concerns about serious and life-threatening side effects. Seroquel is only approved in Canada to treat bipolar disorder and schizophrenia. In the United States, however, it is also used as an add-on treatment to an antidepressant for patients with major depressive disorder. According to IMS Health Canada, a company that tracks the health care industry, the number of prescriptions for Seroquel in Canada has risen from 4.1 million in 2008 to 7.4 million in 2013. However, the prescriptions for the drug are vastly disproportionate to the number of Canadians suffering from ... Read More

Painkiller recalled due to improper expiration dates on label

Syringe - Insulin - Diabetis

Sagent Pharmaceuticals has issued a nationwide recall on a painkiller. Three lots of Ketorolac Tromethamine Injection, a nonsteroidial anti-inflammatory drug, were recalled because the medications were printed with the incorrect expiration date. The labeled date is longer than the known stability of the drug. Ketorolac Tromethamine is used short-term in postoperative patients to treat moderately severe acute pain that requires analgesia in patients already using opioid painkillers. The affected lots include 30mg/mL single-dose vials with the NDC numbers 25021-701-01 and 25021-701-02. Affected lot numbers include MP5021, MP5024, and MP5025 and were distributed to hospitals, wholesalers and distributors across the country ... Read More

Women should not be treated with testosterone therapy, Endocrine Society advises

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Low testosterone is not a valid diagnosis in healthy women, and most women with low amounts of the hormone should not use testosterone-replacement drugs, the Endocrine Society said in a new guideline. “Although limited research suggests testosterone therapy in menopausal women may be linked to improved sexual function, there are too many unanswered questions to justify prescribing testosterone therapy to otherwise healthy women,” guideline task force chair Dr. Margaret Wierman, of the University of Colorado, said in news release. Dr. Wierman said that in a review of past studies, women who had low testosterone levels did not exhibit any signs ... Read More

Merck’s once-weekly diabetes drug as effective as Januvia

januvia - sitagliptin

Merck’s new, once-weekly experimental type 2 diabetes treatment was found in recent clinical trials to have a similar safety and efficacy profile compared to Merck’s sitagliptin, marketed under the brand name Januvia. The study involving the new omarigliptin randomly assigned participants with type 2 diabetes into one of three groups – once-weekly omarigliptin 25 mg; once-daily Januvia 50 mg; or placebo. A mixed-meal tolerance test was performed the day before the study drugs were administered and again at 24 weeks, 1 day after the last dose of Januvia, or 7 days after the last dose of omargliptin. Researchers found that ... Read More

Plaintiffs want information on cases of pancreatic cancer associated with type 2 diabetes drugs

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A federal judge denied plaintiffs’ motion to gather drug companies’ analysis of pancreatic cancer cases among users of their type 2 diabetes drugs; however, his decision is still pending regarding plaintiffs’ request to gather adverse event reports involving those drugs submitted to the U.S. Food and Drug Administration (FDA). U.S. District Judge Anthony Battaglia is presiding over a multidistrict litigation (MDL) involving about 460 plaintiffs who allege they developed pancreatic cancer after taking one of four drugs in a class of type 2 diabetes drugs known as incretin mimetics. The lawsuits name Amylin Pharmaceuticals and Eli Lilly & Co., for the drug Byetta; Merck ... Read More

First-in-class cholesterol drug faring well in clinical trials

lipitor

A first-in-its-class cholesterol-lowering drug is plowing through clinical trials and appears to lower LDL levels significantly more than Merck & Co’s Zetia. ETC-1002 is an oral pill made by Esperion Therapeutics. It is the first in a new class of cholesterol-lowering drugs known as ACL inhibitors. They work by reducing cholesterol synthesis in the liver and increasing LDL receptors that remove cholesterol from the blood. ETC-1002 was pitted against Zetia in a 12-week study involving 348 patients with high LDL, considered the “bad” cholesterol. ETC-1002 reduced LDL an average of 30 percent in patients who received a 180-milligram dose and ... Read More

New drug information database aims to help consumers understand risks and benefits

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Last week, former Wired editor Thomas Goetz and Google engineer Matt Mohebbi introduced health care leaders to their new health information resource, which offers an easy-to-use database of drug information by combining the worlds of technology and health. Their company, called Iodine, seeks to serve the public by offering “better information about thousands of drugs, built from clinical research and real life experience from people like you.” Iodine’s database allows users to enter drugs of interest into a search engine, then presents basic information about the searched drug, its purpose, how it works, reported side effects, warnings, upsides and downsides ... Read More