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SJS 123 articles

Water pill linked to hearing impairment, deafness

The prescription “water pill” Lasix (furosemide) has updated its safety label to include warnings of hearing impairment and deafness. The label changes were approved by the Food and Drug Administration (FDA) and will go into effect immediately. Lasix is a potent diuretic that is used to reduce the swelling and fluid retention caused by various medical problems including heart or liver disease. It is also used to treat high blood pressure. It works by prompting the kidneys to get rid of unneeded water and salt from the body into the urine. The medication comes in both tablet and liquid form ... Read More

FDA considers expanding indication for Cymbalta; side effects SJS, TEN

A Food and Drug Administration (FDA) advisory committee has narrowly voted to recommend that the indication for Eli Lilly’s antidepressant Cymbalta (duloxetine) be expanded to include use as a treatment for chronic musculoskeletal pain. The Anesthetic and Life Support Drugs Advisory Committee also voted that the benefits were minimal but outweighed the risks, which includes a black box warning of suicidality in children, adolescents and young adults; a potential for liver damage; and a risk of developing the rare skin disease Stevens Johnson Syndrome (SJS) and its more serious form, toxic epidermal necrolysis (TEN). Cymbalta is a serotonin-norepinephrine reuptake inhibitor ... Read More

Cause of teen’s TEN remains a mystery

“For me, just being here alive is a story to tell,” Karyl Bell told WNYT-TV. In October 2009, the then-17-year-old unexpectedly developed a rash on her face. Her tongue swelled and she had trouble swallowing and breathing. Her condition quickly worsened. Red, painful blisters broke out on her body. Lesions in her eyes caused her eyes to swell shut. All doctors could tell her worried mother was to sit by as the reaction ran its course and, “hope for the best.” Karyl was eventually diagnosed with toxic epidermal necrolysis (TEN), the most severe form of Stevens Johnson Syndrome (SJS), a ... Read More

Baby Julie mystery kicks off SJS awareness month

Discovery Channel viewers who watched a recent episode of Mystery Diagnosis were as stumped as doctors when the show featured the case of Baby Julie, a 10-month-old who began taking anti-seizure medication after suffering two seizures. Shortly afterward, her eyes swelled shut and she developed strange blisters on her back. She was diagnosed with conjunctivitis, or red eye, in both eyes and the common childhood virus, chickenpox. But her condition worsened. Mystery Diagnosis usually ends each episode with a solid diagnosis and summary on the patient’s prognosis. But the Baby Julie story had no resolution, which prompted viewers to research ... Read More

Dilantin, Lamictal carry risk of serious skin condition called SJS

The Epilepsy Foundation is warning people who take Dilantin or Lamictal to control their seizures that the medications can cause users to suffer from a rare but serious skin condition known as Stevens Johnson Syndrome (SJS). SJS and its more severe form, toxic epidermal necrolysis (TEN), have been associated with thousands of medications, most notably ibuprofen and anti-seizure drugs. The condition often begins with a fever, sore throat and burning eyes and is followed by a rash. The rash spreads and begins to blister, which causes the skin to peel off. This extremely painful condition requires immediate medical attention. Patients ... Read More

SJS survivor hopes more doctors will learn about rare allergic reaction

Kisandra said she felt like a lab rat the day a team of doctors studied the blisters that had sprung up all over her body and pored through thick medical books trying to find what had made her sick. She had just been given Biaxin, an antibiotic, to treat a stomach ulcer. Shortly after starting the medication she developed a fever and blisters on her face, arms, torso and hands. “I had problems focusing and staying awake. My chest hurt so bad like my insides were on fire,” Kisandra wrote on the Stevens Johnson Syndrome (SJS) Foundation support group forum. ... Read More

Woman vows to ‘out race’ effects of Stevens Johnson Syndrome

On September 21, 2008, Kendra Schmidt was pushed in a wheelchair through the track of the Fox Cities Marathon. “My sister ran it that year and my husband (Mike) pushed me,” she told the Post Crescent. But Kendra was determined. “I knew I’d run in it eventually.” It was a tall order for the young woman who at the time was in physical therapy three times a week. Just three months earlier she had suddenly and unexpected developed a severe reaction to a new prescription medication. A rash developed over 95 percent of her body and nearly all of her ... Read More

Glaucoma medication linked to SJS

The Centers for Disease Control (CDC) is warning the public about a medication used to treat a type of glaucoma because users could develop a serious and life threatening allergic reaction known as Stevens Johnson Syndrome (SJS). Neptazane (methazolamide) is a sulfonamide derivative available as 25 mg and 50 mg tablets used in the treatment of an eye condition called open-angle glaucoma. This type of glaucoma is caused by a gradual blockage of the outflow of fluid in the front compartment of the eye over a period of years, causing a slow rise in pressure. It is also used in ... Read More

MMRV vaccine linked to serious skin reaction known as SJS

The Centers for Disease Control (CDC) has issued a warning about the childhood MMRV vaccine for measles-mumps-rubella-chickenpox, saying it may cause the painful and life-threatening allergic reaction known as Stevens Johnson Syndrome (SJS) as well as other serious reactions. ProQuad is the trade name for the MMRV vaccine produced by Merck Pharmaceuticals. It is typically given to children between 1 and 2 years of age. Children in this age group are usually given the MMRV or the three-in-one MMR (measles-mumps-rubella) plus the chickenpox vaccine. The MMRV vaccine made headlines recently because it has been associated with a higher incidence of ... Read More

Pepcid linked to serious skin reaction

Famotidine, the heartburn drug most known by the brand name Pepcid, is yet another drug that has been linked to a deadly skin reaction known as toxic epidermal necrolysis (TEN), the most serious version of Stevens Johnson Syndrome (SJS). Famotidine is available by both prescription and over-the-counter in either a tablet or suspension (liquid) that is taken by mouth. It is in a class of medications called H2 blockers and works by decreasing the amount of acid made in the stomach. Famotidine is used to treat ulcers, gastroesophageal reflux disease (GERD), and conditions where the stomach produces too much acid. ... Read More