Tagged Articles

SSRIs 18 articles

Antidepressants linked to brain hemorrhages

People who take SSRIs and other antidepressants with strong inhibition of serotonin reuptake are at an increased risk of developing a brain bleed, according to a new study published in JAMA Neurology. SSRIs, or selective serotonin reuptake inhibitors, are among the most prescribed medications in the United States, and include brand names such as Zoloft, Paxil, Lexapro, Celexa and Prozac. The medications are most often used for depression; however, SSRIs are often used off-label for other treatments, such as to promote motor recovery after stroke. “Therefore, understanding the potential neurologic risks and possible interactions with other commonly used stroke prevention ... Read More

Antidepressants linked to first-time micro brain bleeds

People who take antidepressants are at an increased risk of developing small, first-time brain bleeds, called cerebral microbleeds, according to a new longitudinal study published in the journal Stroke. Cerebral microbleeds are generally associated with aging, dementia, and cerebrovascular disease. They may predict future brain hemorrhage risk, and may contribute to cognitive impairment, dementia and depression. Researchers noted that the associations were similar for different categories of antidepressants users, and persisted even after adjusting for depressive symptoms and cardiovacsluar risk. For the new study, researchers evaluated 2,550 people age 45 years and older who did not have a history of ... Read More

Judge refuses to dismiss Prozac birth defects lawsuit

A lawsuit filed by a woman who claims taking Eli Lilly & Co.’s antidepressant Prozac during pregnancy caused her child to be born with a heart defect will move forward after an Alabama federal court refused the drug company’s motion to dismiss the case. U.S. District Judge Keith Watkins found that the plaintiff, Dana Fields, had a genuine dispute against Eli Lilly, and that she could show factual causation that her doctor would not have prescribed the drug to her had he known the risks, even though the doctor is now deceased. Fields claims that in 1996 she took Prozac ... Read More

Older antidepressants Prozac, Paxil linked to birth defects

The antidepressants Prozac and Paxil are more likely to cause birth defects in babies born to women who use the drugs while pregnant than newer antidepressants in the same class, according to a study published recently in the British Medical Journal. Prozac and Paxil are in a class of antidepressant drugs known as selective serotonin reuptake inhibitors, or SSRIs. Makers of these medications face thousands of lawsuits from women who claim they were not warned that using the drugs while pregnant could cause birth defects, including a lung defect known as persistent pulmonary hypertension of the newborn (PPHN), heart defects, ... Read More

Prolonged use of Tylenol during pregnancy linked to birth defects in male babies

Tylenol and other medicines containing acetaminophen have long been considered a safe painkiller for pregnant women, but a new study from the University of Edinburth has found that prolonged use of acetaminophen – also known as paracetamol – during pregnancy can drive down testosterone levels in those taking the medicine leading to reproductive disorders in male babies. Researchers gave laboratory mice three doses of acetaminophen every day for a week, and found that the mince given acetaminophen had a 45 percent reduction in testosterone compared to mice who were not given the medicine. Testosterone is produced in the testicles and serves ... Read More

Celexa, Lexapro birth defects lawsuits returned to state court

Fifteen lawsuits over birth defects in children born to women who took the antidepressants Celexa or Lexapro while pregnant were remanded to state court, a federal judge in Camden, N.J., ruled. Attorneys for the drugs’ maker Forest Laboratories unsuccessfully argued that federal jurisdiction was proper because there were questions about the Food and Drug Administration’s (FDA) labeling of the drugs. Defendants’ claims that Forest Research Institute was fraudulently joined as a defendant were rejected as well. The 15 lawsuits are among 20 that were filed in state courts in New Jersey and removed to federal court by the drug companies. ... Read More

New study suggests SSRI use during pregnancy increases risk of autism spectrum disorders in children

Women using antidepressants known as SSRIs (selective serotonin reuptake inhibitors) during pregnancy may be at higher risk of having children with autism spectrum disorders, according to a new study published in the Journal of Autism and Developmental Disorders. Several studies have raised red flags with the use of SSRIs during pregnancy. SSRIs, which include the brand names Zoloft, Paxil, Lexapro, Celexa and Prozac, have been linked to birth defects such as persistent pulmonary hypertension, heart defects, neural tube defects and malformations. Studies have also suggested that children exposed to SSRIs in utero are more likely to have behavioral problems and ... Read More

Study: Children exposed to SSRIs in utero at greater risk for obesity, type 2 diabetes

Babies born to women who took antidepressants while pregnant are more likely to become obese and develop type 2 diabetes, according to a new study. Obesity and type 2 diabetes in children is already on the rise in the United States and is generally blamed on poor diets and reduced physical activity. However, researchers with McMaster University say that maternal antidepressant use may also be a contributing factor in the pediatric obesity and diabetes epidemic. The study focused on a commonly prescribed type of antidepressant known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand names Prozac, Lexapro, ... Read More

Warnings of teen suicide risk with antidepressants may have led to increase in teen suicide attempts

Researchers are concerned that recent warnings about antidepressants increasing suicide risk in teens may have contributed to a rise in teen suicide attempts. The study, published in the British Medical Journal, set out to investigate this possible power of suggestion since 2003, when the Food and Drug Administration (FDA) began publicizing suicide risks (including suicide attempts and completed suicides) with antidepressant use in young adults. The study involved data from about 2.3 million adolescents and young adults. Researchers found that the warnings led to a significant drop in antidepressant use in young people, beginning in 2003. At the same time, ... Read More

Forest to pay millions to Missouri parents for misleading drug data on childhood depression meds

Forest Laboratories will pay between $7.7 million and $10.4 million to settle multidistrict litigation alleging the drug company misled Missouri parents into buying Celexa and Lexapro for their children even though the antidepressants were not approved for children. The class includes all parents and other third parties in Missouri who purchased Celexa for a minor patient between Jan. 1, 1998, and Dec. 31, 2013, or Lexapro for a child between Aug. 1, 2002, and Dec. 31, 2013. Forest is accused of covering up clinical trial data that showed Celexa was ineffective in treating pediatric depression based on studies from as ... Read More