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Stevens Johnson Syndrome 124 articles

Contrast agent linked to serious skin reactions

The safety label for the medical contrast agent Optiray (ioversol) is being updated under the Warnings and Precautions section to include the risk of severe cutaneous adverse reactions (SCAR), which may develop from one hour to several weeks after intravascular contrast agent administration, the Food and Drug Administration (FDA) announced. “These reactions include Stevens-Johnson Syndrome and toxic epidermial necrolysis (SJS/TENS), acute generalized Exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Reaction severity may increase and time to onset may decrease with repeat administration of contrast agent,” the updated label states. Optiray is a radiopaque contrast agent ... Read More

High court upholds $140 million verdict involving Children’s Motrin injuries

The U.S. Supreme Court denied Johnson & Johnson’s petition to have a $140 million jury verdict reviewed in a failure-to-warn case involving a teenage girl who developed a serious skin reaction blamed on the company’s Children’s Motrin. Johnson & Johnson had argued that claims made by Samantha Reckis and her parents that the over-the-counter painkiller gave her a painful and blistering skin condition should have been preempted by the 2009 Supreme Court decision in Wyeth v. Levine, which found that drug makers cannot be held liable for not including a label that “clear evidence” indicates the FDA would not have ... Read More

McNeil denied appeal in $10 million Children’s Motrin verdict

The Pennsylvania Supreme Court refused to hear an appeal by Johnson & Johnson unit McNeil-PPC Inc., of a $10 million verdict levied against the company by the family of a girl who suffered a serious allergic reaction and blindness after taking Children’s Motrin as prescribed for fever. McNeil had petitioned the state high court to hear the case after its bid for appeal was rejected by the Pennsylvania Superior Court panel last September. The panel supported the lower court’s decision in July, which found the consumer health care company failed to warn that its over-the-counter medicine could cause the serious ... Read More

Woman suffers Stevens Johnson Syndrome, burning ‘from inside out’ after taking a friend’s medication

A young mother is fighting for her life after taking a friend’s prescription antibiotic and suffering an allergic reaction that doctors say is causing her to burn from the inside out. Yassmeen Castanada took the antibiotic on Thanksgiving to help ward off a sickness she felt coming on. But shortly afterward her eyes, nose and throat began to burn. She was rushed to the emergency room where her condition progressed. Within days, blisters covered her body and her skin began to peel off in sheets, causing excruciating pain and exposing her to life-threatening infection. The diagnosis – Stevens Johnson Syndrome ... Read More

McNeil loses appeal on $10 million Children’s Motrin judgment

Johnson & Johnson subsidiary McNeil-PPC failed to convince the Pennsylvania Superior Court to overturn a $10 million verdict alleging the company’s Children’s Motrin caused a girl to develop a life threatening condition that burned her skin and caused her to go blind. McNeil argued that there was no evidence to show that the company’s failure to warn consumers of the risk of the serious allergic reaction on the drug’s safety label led to the the girl’s injuries. Brianna Maya was 3 when her mother gave her Children’s Motrin over the course of four days to treat a fever and cough. ... Read More

Skin reaction warning added to Excedrin Migraine over-the-counter pain reliever

Safety labels of over-the-counter pain reliever Excedrin Migraine have been updated to include a warning for serious skin reactions, the Food and Drug Administration (FDA) announced. Symptoms of this allergic reaction include skin reddening, blisters and rash. Consumers who use this medicine and develop a skin reaction are advised to stop use and seek medical attention right away. Excedrine Migraine contains 250 mg acetaminophen, 250 mg aspirin and 65 mg caffeine. This combination of drugs is used to treat pain caused by tension headaches, migraine headaches, muscle aches, menstrual cramps, arthritis, toothaches, the common cold, and nasal congestion. In 2013, ... Read More

FDA warns of rare but serious skin reactions with painkiller acetaminophen

The widely used fever reducer and painkiller acetaminophen can cause rare but serious and potentially life threatening skin reactions, warns the Food and Drug Administration (FDA). Acetaminophen has been available for decades and is available both by prescription and over-the-counter. Tylenol is one brand name of the pain reliever, but it is also available in generic versions and as well as in combination with other medicines including opioids for pain, and medicines to treat colds, coughs, allergy, headaches, and sleeplessness. Skin reactions to acetaminophen are rare but include three serious skin diseases with symptoms that range from rashes and blisters to widespread ... Read More

Smoking cessation drug Aplenzin carries risk of suicidal thoughts, mental problems

A new black box warning has been added to the antidepressant Aplenzin informing  patients of suicidal thoughts and neuropsychiatric reactions in those who use the drug to help them stop smoking. Aplenzin contains the active ingredient bupropion hydrobromide, which is also found in the brand-name drugs Budeprion, Buproban, Forfivo, Wellbutrin and Zyban. Aplenzin and Wellbutrin are indicated for depression. Some dosages of Wellbutrin are also used to treat seasonal affective disorder. Zyban is prescribed to help people quit smoking. Doctors have the discretion to prescribe drugs for uses other than those on the drug’s label. The new boxed warning for ... Read More

New warning of serious skin rash issued for antidepressant Paxil

A new side effect has been added to the safety label of the antidepressant Paxil (paroxetine) following reports that some patients who used the drug developed a rare but life-threatening rash known as Stevens Johnson Syndrome (SJS). Paxil is in a class of medications known as selective serotonin reuptake inhibitors, or SSRIs. Other drugs in this class include Zoloft, Celexa, Lexapro and Prozac. SSRIs are among the most prescribed medications in the United States and are used to treat depression and anxiety. SJS is an allergic reaction to medication. It is most often liked to anti-inflammatory drugs and antibiotics. The ... Read More

New warnings on anti-epilepsy drug Keppra

New warnings and precautions have been added to the safety label of the anti-epileptic drug Keppra (levetiracetam), alerting patients to possible adverse reactions ranging from psychiatric problems to serious skin reactions. Keppra is an anti-convulsant medication commonly used to treat patients who suffer from seizures related to epilepsy and other disorders. The medication comes in both brand-name and generic versions and is sold in both tablet and oral solution form. The new safety labels were approved last month by the Food and Drug Administration (FDA). New warnings on Keppra include the risk for psychiatric symptoms including aggression, agitation, anger, anxiety, ... Read More