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stroke 225 articles

FDA questions value of aspirin therapy for heart attack prevention

The Food and Drug Administration (FDA) last week denied a request by German drug maker Bayer AG to change the label on packages of its aspirin to promote the benefits of regular aspirin therapy to ward off first heart attack or stroke in people who have never had cardiovascular problems. Now the agency is questioning whether the treatment carries any value to those with no heart issues and whether taking a daily aspirin may actually put these individuals at risk for potentially serious side effects. Aspirin therapy is often recommended for people with cardiovascular disease because it reduces the clotting ... Read More

Physicians question safety of testosterone replacement therapy

Increasing numbers of physicians are questioning whether testosterone replacement therapy to boost libido, muscle mass and mood may do more harm than good. Recent studies have linked testosterone therapy to an increased risk of heart attack, stroke and death. News of the study results rang loudly throughout America, where nearly 3 percent of men older than 40 are using prescription testosterone supplements as a “fountain of youth.” And they didn’t come blindly to their doctors in search of a cure. Many were swayed by heavy marketing campaigns waged by drug companies concocting a disorder they called “Low T,” and urging men ... Read More

Type 2 diabetes may shrink brain tissue, lead to cognitive disorders

Long-term type 2 diabetes may shrink gray matter, the portion of the brain responsible for memory, emotions, decision-making and self control, according to a new study published in the journal Radiology. For each decade a person has diabetes, his brain looks about two years older than a non-diabetic, researchers found. For the study, researchers with the University of Pennsylvania analyzed MRI scans to evaluate brain structure of more than 600 patients with type 2 diabetes. They were surprised to find that diabetes was not linked to just the damaging effect of the tiny blood vessels in the brain, but by ... Read More

New questionnaire designed to help identify Low T in men

A new assessment tool may help physicians screen men for low testosterone, according to a new study published in the Journal of Men’s Health. The male androgen deficiency syndrome (MADS) questionnaire, developed by researchers at Icahn School of Medicine in New York, is designed to be a more simplified screening tool to help doctors and patients identify patients at risk for hypogonadism, or low testosterone. The new questionnaire was used on 5,071 men from 44 centers in September 2010 and 2011. Nearly two-fifths of the men were identified as having a testosterone deficiency. These men were also more likely not ... Read More

FDA warns of serious risks associated with epidural injections of corticosteroids

Injections of corticosteroids into the epidural space of the spine may cause rare but serious side effects including vision loss, stroke, paralysis and death, the Food and Drug Administration (FDA) warned. The injections are given to treat neck and back pain, and radiating pain in the arms and legs. However, the effectiveness and safety of epidural administration of corticosteroids has not been established and the FDA has not approved corticosteroids for this use. The agency is requiring warnings be placed on the safety labels of injectable corticosteroids to explain these risks to health care providers and patients. While the FDA ... Read More

Could ‘Low T’ treatments be dangerous to your health?

If you’re a man and you listen to the advertisements from some drug makers describing a condition known as “Low T” with symptoms such as low libido, zapped energy levels, weight gain and muscle loss, you might be tempted to take the drug maker’s advice and check with your doctor to see if you could be a candidate for testosterone replacement therapy. Who wouldn’t want to look better, feel better, and have that spring in your step again? However, the drugs may be too good to be true, according to a study recently published in the Journal of the American ... Read More

Repros enrolls men to test new topical testosterone treatment Androxal

Repros Therapeutics Inc. announced it has completed enrollment for one of two clinical trials pitting its topical testosterone gel alternative Androxal against other topical testosterone products currently on the market. Each trial will include 120 men, who will be divided into groups of 40 for three parallel study arms to test Androxal against an already marketed testosterone gel and a placebo. Studies will run for 17 weeks, which includes 16 weeks of dosing and one week of follow-up to gather information for the conclusion. Repros sought men who were at least 60 years of age who exhibited a normal sperm count ... Read More

Study: Low T contributes to more satisfying relationships

Low testosterone levels in men have been blamed for a variety of symptoms – from low sex drive and mood swings to weight gain and muscle loss. But a new study shows that low testosterone has its benefits. It may actually contribute to more romantic and satisfying relationships. “The assumption is generally that high testosterone is good for sexual relationships,” says Robin Edelstein, associate professor of psychology with the University of Michigan. Edelstein and her team set out to put that notion to the test. They surveyed 39 heterosexual couples between the ages of 18 and 39 who were in relationships ... Read More

Doctor raises red flags regarding heart risks with testosterone therapy

Testosterone replacement therapy may sound attractive with ads promising to build muscle mass and boost libido, but Low T therapy may not be all that it’s cracked up to be, warns Dr. Joe Littlejohn, a urologist at Orlando Health. It could be deadly. If you listen to the advertisements from drug companies pushing testosterone products, such as AndroGel, Testim and Axiron, the therapy can help men feel decades younger. Though testosterone levels drop naturally as men age, these supplements can help men turn back the clock. What’s not to love? New research, however, has raised some serious red flags that ... Read More

More lawsuits filed against makers of testosterone replacement therapies

Makers of testosterone treatments are being slapped with lawsuits following studies that show use of the products increases the risk of cardiovascular events. The latest lawsuits to be filed name Auxilium Pharmaceuticals and GlaxoSmithKline, makers of Testim, as well as Abbott Laboratories and AbbeVie, makers of AndroGel. A lawsuit filed by Robert Olivetti and his wife Marion allege that Mr. Olivetti’s use of Testim and AndroGel caused him to have a heart attack, which led to a coronary bypass. Edwin Rios and wife Eileen lawsuit claim Mr. Rios’ use of Testim caused his heart attack. The plaintiffs say the drug ... Read More