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suicide attempts 7 articles

Levaquin label updated to include ‘attempted suicide,’ ‘completed suicide’ risks

The safety label of the antibiotic Levaquin has been updated to include new warnings involving the risk of suicidality, according to a Food and Drug Administration (FDA) Safety Label Changes update. Levaquin, known generically as levofloxacin, is in a class of drugs called fluoroquinolones, which are known to increase the risk of central nervous system effects including convulsions and toxic psychoses, and may cause central nervous system stimulation which may lead to anxiety, tremors, restlessness, lightheadedness, hallucinations, paranoia, depression, nightmares, insomnia, and suicidal thoughts. The labels have been updated to include the risk for attempted suicide and completed suicide, “especially ... Read More

Lawsuit blames antidepressant Paxil for man’s suicide

U.S. District Judge James B. Zagel declined motions for a summary judgment by the defendant and ruled that a lawsuit blaming drugmaker GlaxoSmithKline (GSK) of manipulating data linking its antidepressant Paxil to suicide should move straight to trial. The lawsuit was filed by Wendy Dolin, widow of Reed Smith LLP attorney Stewart Dolin, who committed suicide shortly after beginning treatment with Mylan Inc.’s generic version of Paxil, known chemically as paroxetine. Mylan is also named in the lawsuit. Dolin claims that GSK attempted to downplay the risks of Paxil in one clinical trial by increasing the number of suicide attempts ... Read More

Bariatric surgery increases risk of self-harm, suicide

People who undergo bariatric surgery to lose weight are at greater risk of harming themselves or attempting suicide two to three years after surgery, a new study has found. The risk is greater among patients who suffered from some kind of mental illness or depression about five years before they underwent the surgery. For many people who are obese, bariatric surgery – a procedure performed on the stomach or intestines to induce weight loss – is a lifesaver, helping them to shed extra weight and in some cases allowing them to wean off medications such as those for type 2 diabetes. ... Read More

Mental health groups ask FDA to remove black box warning for suicide risk from antidepressants

Mental health experts are petitioning the Food and Drug Administration (FDA) to remove its severest warning involving suicidal thoughts from the safety labels on all antidepressants because the warning has resulted in a 33 percent increase in suicide attempts, and has scared away some patients who may benefit from the medication. In 2004, the FDA placed a black box warning, its most serious kind, on all categories of antidepressants, indicating that there is an increased suicide risk in children and adolescents treated with the drugs. Two years later, the FDA extended the warning to young adults to age 25 and recommended ... Read More

Warnings of teen suicide risk with antidepressants may have led to increase in teen suicide attempts

Researchers are concerned that recent warnings about antidepressants increasing suicide risk in teens may have contributed to a rise in teen suicide attempts. The study, published in the British Medical Journal, set out to investigate this possible power of suggestion since 2003, when the Food and Drug Administration (FDA) began publicizing suicide risks (including suicide attempts and completed suicides) with antidepressant use in young adults. The study involved data from about 2.3 million adolescents and young adults. Researchers found that the warnings led to a significant drop in antidepressant use in young people, beginning in 2003. At the same time, ... Read More

Doctors need training to identify suicide risk among TBI patients

More and more studies show that people who suffer from traumatic brain injuries (TBI) are at greater risk of suffering from depression and mood changes that can lead to suicidal ideation. An Australian study suggests that doctors may play a pivotal role in preventing suicide among people with these injuries. Several population-based studies have shown that people with severe TBI are four times more likely to commit suicide compared with the general population, and people with mild injuries (ie, concussion) also have an elevated risk of suicide. Epidemiological research has also found that people with TBI (all severity levels) had ... Read More

FDA approves COPD drug despite potential risk for cancer, suicidality

A new drug to prevent exacerbations of COPD has been approved by the Food and Drug Administration (FDA) even though an FDA advisory committee voted not to recommend the approval for the drug because its “modest” benefits were outweighed by serious side effects including the potential for cancer and psychiatric events including suicide. Phosphodiesterase-4 inhibitor roflumilast (Daliresp) was voted down 10-5 by the FDA’s Pulmonary-Allergy Drugs Advisory Committee a year ago based on clinical studies that showed 14 percent of patients discontinued the drug because of problems ranging from weight loss, diarrhea, and nausea. What raised the biggest red flags ... Read More