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tar dive dyskinesia 3 articles

Generic drug makers failed to warn about side effects from heartburn drug Reglan

A Missouri appeals court upheld claims by two women that makers of generic versions of the heartburn drug Reglan failed to update their safety labels to warn about side effects associated with long-term use of the medication. Reglan, which is sold generically under the name metoclopramide, has been linked to a movement disorder known as tardive dyskinesia. In 2004, manufacturers of brand-name Reglan updated its safety label with the approval of the Food and Drug Administration (FDA) to warn that “Therapy should not exceed 12 weeks in duration.” Generic manufacturers were required to update their safety labels as well but ... Read More

AL Supreme Court rules: Brand name drug makers liable for warnings on generic drug counterparts

Makers of brand-name medications can be held liable for warnings on generic drugs even if the generic was produced by another drug company, the Alabama Supreme Court ruled. A majority of the nine-member court upheld a 2013 decision, which was viewed as a defeat by business leaders in this mostly Republican state. The ruling is based on a federal lawsuit filed by Danny and Vick Weeks against five current and former drug makers alleging that long-term use of the heartburn drug metoclopramide, which was also sold under the brand name Reglan, caused a debilitating movement disorder known as tardive dyskinesia. ... Read More

Experimental drug helps reduce symptoms of tardive dyskinesia

Patients with a movement disorder known as tardive dyskinesia saw a reduction in spasms after taking Neurocrine Biosciences’ experimental drug NBI-98854 for six weeks compared to patients taking a placebo. The drug company says it hopes the promising data will win Food and Drug Administration (FDA) approval to move forward with a late-stage study during the first half of the year. Tardive dyskinesia is a difficult to treat and often incurable neurological disorder that causes involuntary movements such as grimacing, tongue movements, lip smacking and puckering, pursing of the lips, and excessive eye blinking. The condition most often occurs as ... Read More