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Treanda 4 articles

Old drug found to be key treatment for non-Hodgkin lymphomas

A drug developed 50 years ago has reemerged as a new weapon in the fight against certain types of non-Hodgkin lymphomas, more than doubling progression-free survival rates and reducing side effects compared to a multi-drug cocktail that for years has been used to treat indolent non-Hodgkin lymphomas. The drug, bendamustine (Treanda), showed promising results when combined with another therapy, rituximab (Rituxan). Traditionally, the disease has been treated with a combination of five different drugs – rituximab, cyclophosphamide (Cytoxan), doxorubicin (Adriamycin), vincristine, and prednisone – called R-CHOP. Findings on bendamustine were presented this week at the annual meeting of the American ... Read More

Cancer drug’s prescribing information to include warning of SJS

A cancer treatment drug approved by the Food and Drug Administration (FDA) to treat chronic lymphocytic leukemia and non-Hodgkin’s lymphoma just last year has been linked to a serious adverse reaction known as Stevens Johnson Syndrome, or SJS, when used in conjunction with another medication. Cephalon, makers of Treanda, has filed documents with the Securities and Exchange Commission this week stating it will update its prescribing information for the Treanda drug to include a warning of the possibility of SJS when used with allopurinol, a medication used to treat excess uric acid in the blood plasma, according to the Philadelphia ... Read More

New labeling for CLL, NHL drug includes TEN warning

The FDA has approved labeling for a drug to treat chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL), to include a warning of a rare but life-threatening reaction to medication known as toxic epidermal necrolysis, also known as TEN, according to MedScape Today. TEN is the most severe form of Stevens Johnson Syndrome, or SJS, a condition that affects the skin and mucus membranes. Rashes appear on the skin and blister over, causing the skin to peel off in sheets. More than 200 drugs are linked to SJS and TEN, the most common being ibuprofen, antibiotics and anti-seizure medicines. The ... Read More