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vicodin 20 articles

Deadly combination of opioids and anti-anxiety drugs prematurely killing more white women

Opioid painkillers and anti-anxiety drugs – which are often prescribed in tandem – are prematurely killing a disproportionate number of white women, according to a Washington Post analysis. The Food and Drug Administration (FDA) just required black box warnings be placed on the safety labels of opioids and anti-anxiety drugs known as benzodiazepines, or “benzos,” explaining that taking the two drugs together was potentially lethal. The warning affected nearly 400 products in total. The Washington Post analysis involved middle-aged participants from the latest National Health and Nutrition Examination Survey and found that white women prescribed the powerful painkillers were five times more likely to also be ... Read More

CDC recommends doctors consider alternatives to opioids for chronic pain

The number of people dying from overdoses of prescription painkillers has skyrocketed in recent years, prompting the Centers for Disease Control and Prevention (CDC) to issue new guidelines that urge doctors to consider alternatives to opioids when treating adults with chronic pain. Deaths from opioids, which include OxyContin and Vicodin, have more than quadrupled since 1999. More than 40 Americans die each day from prescription opioid overdoses. “We must act now,” said CDC Director Dr. Tom Frieden, who put the burden on prescribing physicians. “Overprescribing opioids – largely for chronic pain – is a key driver of America’s drug-overdose epidemic.” ... Read More

Tylenol shown ineffective for back, arthritis pain relief

The popular over-the-counter painkiller Tylenol is no more effective as a placebo in treating back pain, knee or hip pain, or arthritis, according to a systematic review of randomized clinical trials. Tylenol contains the active drug ingredient acetaminophen, which is also available in various OTC brands as well as in greater doses and/or in combination with other drug ingredients in many prescription medications. The review, conducted by Australian researchers, involved three randomized trials that pitted the effects of acetaminophen against a placebo for spinal pain, and 10 trials evaluating the drug for relieving the pain of osteoarthritis. In total, the analysis ... Read More

DEA introduces new drug take-back program to combat prescription drug abuse

A new Drug Enforcement Administration (DEA) rule aims to combat a growing epidemic of prescription drug addiction and abuse by authorizing pharmacies, hospitals, clinics, and others to serve as drop-off sites for unused prescription medications. Attorney General Eric Holder said that the new regulation will help save lives and protect families from the dangers of prescription drug misuse. In 2011, unintentional prescription drug overdoses accounted for more than half of the 41,300 drug overdose deaths in the U.S. Prescription opioids, which are increasingly prescribed for pain relief, are particularly addictive and likely to be abused. Opioid pain killer overdose caused ... Read More

FDA revokes approval for seven painkillers containing acetaminophen

The U.S. Food and Drug Administration (FDA) has revoked approval for seven narcotic painkillers containing acetaminophen, including versions of AbbVie Inc.’s Vicodin. The agency has done this in response to recent concerns about these drugs’ potential of causing liver damage. Just three years earlier, regulators announced a plan to cap the amount of acetaminophen allowed per dose to 325 milligrams. Three versions of Abbvie’s Vicodin that combine acetaminophen and hydrocodone were affected by this. Also, companies such as Actavis Inc., Nesher Pharmaceuticals USA LLC, West-Ward Pharmaceutical Corp, and Leitner Pharmaceuticals LLC, that all made products containing acetaminophen had those product ... Read More

Federal judge blocks Massachusetts ban of new painkiller Zohydro

Drug maker Zogenix Inc., won another battle in its war to get its controversial painkiller Zohydro on the market. This week, a Massachusetts federal judge blocked plans by Massachusetts Gov. Deval Patrick to ban prescriptions and sales of the newly approved narcotic in the state in an attempt to curb a growing trend of prescription drug abuse. Zogenix filed a lawsuit alleging the move was unconstitutional. U.S. District Judge Rya Zobel ruled that the ban conflicted with federal laws, which take precedence against state laws when the two are in conflict. The U.S. Food and Drug Administration (FDA) approved Zohydro ... Read More

Legislation aims to revoke FDA’s approval of new opioid Zohydro

A group of lawmakers concerned about health risks and a growing epidemic of prescription drug abuse has introduced legislation to revoke the Food and Drug Administration’s approval of the new, highly potent opioid painkiller Zohydro ER. “I have tried reasoning with the FDA, and I’ve repeatedly requested the agency change its course on this dangerous drug. Their refusal to budge forces me to introduce legislation,” Sen. Joe Manchin, D-W.Va., said in a statement. He teamed up with Rep. Stephen Lynch D-Mass, and Rep. Hal Rogers, R-Ky., on the bill. Zohydro ER is the first pure hydrocodone drug to be approved ... Read More

Potent Zohydro painkiller faces more hurdles as it enters market

The fate of the newly approved, potent opioid painkiller Zohydro continues to hang in the balance. The drug is expected to hit the market later this month despite petitions from physician groups, consumer watchdog groups, addiction counseling groups, and even a team of attorneys general urging the Food and Drug Administration (FDA) to rethink its recent approval of the drug. Two senators have also requested an investigation into whether pay-for-play practices played a role in the approval of Zohydro. Now, the painkiller faces another challenge: the makers of OxyContin say they have completed testing of an abuse-resistant version of the ... Read More

Attorneys general ask FDA to rethink its approval of first single-ingredient hydrocodone painkiller

Twenty-eight attorneys general are calling for the removal of powerful new painkiller Zohydro, arguing that the narcotic would only add to the national epidemic of prescription drug abuse. Zohydro, the first and only single-ingredient hydrocodone painkiller approved by the Food and Drug Administration (FDA), was granted clearance by the agency in October. It is an extended release formulation that is considered five to 10 times more potent than hydrocodone combination pill such as Vicodin. The state prosecutors are asking the FDA to either revoke the drug’s approval or require the drug maker Zogenix to change the formulation so that it ... Read More

FDA approves pure form of painkiller hydrocodone, deemed stronger than Vicodin

Just days after the Food and Drug Administration (FDA) proposed stricter rules for drugs containing hydrocodone – such as Lortab and Vicodin – to help curb the growing epidemic of prescription drug abuse, the agency announced that it has approved a purer form of hydrocodone that is even stronger than other drugs in its class. The FDA approved Zohydro ER to treat pain severe enough to require around-the-clock, long-term treatment. The drug is approved for patients for whom alternative treatment has proved inadequate or ineffective. The FDA did require the drug’s maker, Zogenix, to conduct post marketing studies for Zohydro ER ... Read More