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Vioxx 20 articles

Common drugs that doctors refuse to take

Just because a medication is approved by the Food and Drug Administration (FDA) does not mean it is safe. In fact, many drugs have been linked to concerning side effects. That’s why it is important for patients to weigh the risks and benefits of all drugs before taking them, including seemingly innocuous over-the-counter medicines. Men’s Health magazine compiled a list of medications that doctors said they wouldn’t take themselves. If you or someone you love is taking any of these, it might be time to discuss your risk with a doctor. Pseudoephedrine – The decongestant that is used to manufacture ... Read More

DEA introduces new drug take-back program to combat prescription drug abuse

A new Drug Enforcement Administration (DEA) rule aims to combat a growing epidemic of prescription drug addiction and abuse by authorizing pharmacies, hospitals, clinics, and others to serve as drop-off sites for unused prescription medications. Attorney General Eric Holder said that the new regulation will help save lives and protect families from the dangers of prescription drug misuse. In 2011, unintentional prescription drug overdoses accounted for more than half of the 41,300 drug overdose deaths in the U.S. Prescription opioids, which are increasingly prescribed for pain relief, are particularly addictive and likely to be abused. Opioid pain killer overdose caused ... Read More

High doses of NSAIDs put users at risk of heart attacks, strokes

Millions of people take nonsteroidal anti-inflammatory drugs (NSAIDs) to treat mild to moderate pain, but new research shows the medication may put users at risk for heart attacks and strokes. NSAIDs are in a class of painkillers that includes the medications aspirin, ibuprofen and naproxen. They are sold over-the-counter in both generic version and brand names such as Advil, Motrin and Aleve. Prescription NSAIDs are also available. The most common side effects associated with the drugs includes stomach upset and ulcers. They may also interfere with kidney function. The new study showed that high doses of these drugs taken regularly can increase ... Read More

Prescription drug deaths rise for 11th consecutive year

The number of prescription drug-induced deaths rose for the 11th straight year, according to a Centers for Disease Control and Prevention (CDC) analysis. Most of the drug deaths were accidents involving potent painkillers such as OxyContin and Vicodin. “This is a big problem that has gotten much worse quickly,” said CDC Director Dr. Thomas Frieden. Prescription drug deaths continue to rise despite efforts to raise awareness of the risks among doctors and patients. The CDC reported a total of 38,329 drug-overdose fatalities nationwide in 2010. Nearly 60 percent of those deaths involved medicines, most of them prescription drugs. In 2009, the ... Read More

Merck seeks approval for previously rejected combination cholesterol drug

Merck & Co. is resubmitting the drug application for its combination cholesterol-lower drug MK-0653C, which was rejected by the Food and Drug Administration (FDA) last March due to insufficient data. The experimental medication combines a generic version of the cholesterol-lowering drug Lipitor, the top-selling medication of all time, with Merck’s cholesterol med Zetia. Lipitor and Zetia work in different ways to reduce high cholesterol and thus reduce the risk of heart attack and stroke. Lipitor, also known as atorvastatin, is a member of the statin drug family, which reduce the amount of cholesterol naturally produced in the liver. Zetia reduces the ... Read More

Big Pharma earns 77,500-percent return on lobbying investments, at taxpayers’ expense

Until November 2010, an opioid painkiller called Darvocet (Dextropropoxyphene) had been prescribed to millions of people since the 1950s, despite its known risks for overdose and heart arrhythmia. It remained on the market for decades, despite multiple attempts by safety groups to ban it. Pfizer’s anti-smoking drug Chantix is aggressively advertised and widely prescribed in the U.S., even though it consistently lands on lists of the most dangerous drugs in the U.S. and receives the FDA strongest possible warnings. DePuy Orthodpaedics manufactures an all-metal hip implant system that scores of patients blame for serious injuries stemming from the device’s early ... Read More

FDA rejects Merck’s new combo cholesterol drug

Merck & Co. will have to provide more data on its experimental cholesterol-lowering drug cocktail before the Food and Drug Administration (FDA) will allow it to be sold in the United States. The drug, known only as MK-0653C, is designed to fight high cholesterol in two different ways to reduce the risk of heart attack and stroke. Merck’s new drug contains a generic version of the statin Lipitor, the top selling drug of all time. Known chemically as atorvastatin, Lipitor works to reduce the amount of cholesterol naturally produced in the liver. MK-0653C also contains Zetia, known as simvastatin, a ... Read More

Do drug companies protect profits by unethical means?

Sometimes it is hard to know whom you can trust. But trust is of the utmost importance when it involves human life. Unfortunately, drug companies are apparently demonstrating they are more interested in profits than in protecting the consumers who use their products. One troubling example is the antidepressant Paxil. The drug is in a class of medications known as selective serotonin reuptake inhibitors (SSRI), which are among the most prescribed medications in the United States. The drug was listed as a Category C pregnancy medication, meaning there was no evidence to show whether the drug was dangerous to developing ... Read More

Prescription drug overdose and abuse now the leading cause of death in U.S.

Public health experts are warning that an epidemic of pharmaceutical drug injuries has broken out nationwide, likely fueled by the ever-growing number of prescriptions written for the relief of pain and anxiety. According to preliminary data from the U.S. Centers for Disease Control and Prevention, the number of drug deaths exceeded the number of traffic fatalities in the U.S. for the first time in 2009, becoming the leading cause of death in the U.S. At least 37,485 people died from prescription drug injuries in 2009 — 1201 more than the number of people killed in traffic accidents during the same ... Read More

Swedish doctor says Darvocet litigation may be bigger than Vioxx trials

The most surprising thing about Darvocet is probably that the now-banned painkiller, a combination of propoxyphene and acetaminophen, stayed on the market for decades even while consumer groups and health advocates warned about its serious health risks. When Darvocet first appeared on the market in the 1950s, it quickly became one the most-prescribed drugs in the United States, and when such a widely used drug is also one of the most dangerous drugs on the market, the extent of the damage done to public health is staggering. Swedish doctor Ulf Jonasson and his wife, Dr. Birgitta Jonasson, who have spent ... Read More