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weight loss 27 articles

FDA approves new type 2 diabetes medication Farxiga

A new drug has been approved by the Food and Drug Administration (FDA) to help regulate blood sugar in patients with type 2 diabetes. Farxiga, developed by AstraZeneca and Bristol-Myers Squibb, has been available in Europe under the name Forxiga. U.S. drug regulators rejected the drug last year because of bladder cancer, heart disease and liver toxicity concerns. Farxiga is the second in a class of drugs known as SGLT2 inhibitors to be approved in the United States. Johnson & Johnson’s Invokana was approved earlier this year. Other drugmakers, including Boehringer Ingelheim, are also developing SGLT2 inhibitors. Drugs in this class ... Read More

Novo Nordisk tests high doses of diabetes drug Victoza as weight loss treatment

Drug maker Novo Nordisk is testing high doses of its type 2 diabetes drug Victoza as a possible treatment for obesity. However, analysts are questioning whether it will work well enough to be a commercial success. Victoza was initially marketed by Novo Nordisk using celebrity chef Paula Deen. The company quickly discontinued the contract with Deen after the Southern chef was heavily criticized for making racist remarks. The drug is in a class of medications known as glucagon-like peptide 1 dugs, or GLP-1. Other drugs in this group include Byetta, made by Bristol-Myers Squibb and AstraZeneca. GLP-1 drugs are in ... Read More

Louisiana files lawsuit against Adderall makers for off-label marketing

Irish drug maker Shire PLC pushed attention deficit hyperactivity disorder (ADHD) drugs for un-approved uses and collected federal Medicare reimbursement for these illegal actions, according to a lawsuit filed by the Louisiana attorney general. The lawsuit alleges that Shire promoted the ADHD drugs Adderall, Adderall XR and Vyvanse for uses that were not approved by the Food and Drug Administration (FDA) such as to treat depression and schizophrenia, and to aid in weight loss. Doctors have the discretion to write prescriptions for drugs for so-called off-label uses but pharmaceutical companies cannot market drugs for uses not approved by the FDA. ... Read More

Diarrhea-causing parasite linked to salad mix sold to restaurants

The outbreak of a diarrhea-inducing parasite that has sickened at least 400 people in 16 states has been traced to prepackaged salad mix served at Olive Garden and Red Lobster restaurants, the Food and Drug Administration (FDA) said. The salad mix was produced by the Mexican subsidiary of Taylor Farms, an American food service company, and sold to the restaurants in various states. The salad mix contained iceberg and romaine lettuce, carrots and red cabbage. FDA investigators are working with the company to conduct an environmental assessment of the processing facility in Mexico to determine the cause of the parasite. ... Read More

Diarrhea-causing parasite spreads across country, contaminated produce suspected

At least 321 people in 14 states and New York City have become infected with Cyclospora, a parasite that can contaminate produce and cause gastrointestinal symptoms in people who consume it. At least 18 people have been hospitalized since the first cases were reported in mid-June. No deaths have been reported. Officials with the Centers for Disease Control and Prevention (CDC) have yet to identify the source of the outbreak, although previous outbreaks have been linked to produce. The parasite is typically found in the tropics and not indigenous to the United States, which suggests the culprit could be produce ... Read More

Number of people and states affected by stomach bug parasite increases

Health officers are still not sure of the source of a parasite that has sickened at least 285 people in 11 states. The parasite, known as cyclospora, is a microscopic protozoa that is commonly linked to fresh produce. The prime suspects are fresh raspberries, basil, snow peas and lettuce, though no specific foods have been identified. People infected with cyclosporasis experience symptoms such as vomiting, diarrhea and weight loss that can last weeks. The illness is easily treated with antibiotics. At least 10 people have been hospitalized, but no deaths have been reported. Cyclosporasis is usually spread through contaminated water. ... Read More

FDA warns against using dietary supplements containing DMAA

The Food and Drug Administration (FDA) is warning consumers that dietary supplements promising weight loss, muscle building and performance enhancement containing dimethylamylamine (DMAA) can be dangerous and even deadly and should be avoided at all costs. The agency is working hard to remove all DMAA-containing supplements from the marketplace, however some companies continue to sell the products illegally. DMAA can elevate blood pressure and could lead to cardiovascular problems including heart attacks, shortness of breath, and tightening in the chest. Given the known biological activity of DMAA, the ingredient may be particularly dangerous when used with caffeine. As of April ... Read More

Canker sore, asthma drug to be tested as a treatment for obesity, diabetes

A drug used to treat canker sores may one day help patients who are obese or have diabetes, a new study suggests. The drug, amlexanox, was found to increase the basal metabolism of laboratory rats and reverse obesity, diabetes and fatty liver. Amlexanox is a medication with antiallergic and anti-inflammatory effects. It is also used in some countries as a treatment for asthma. Based on the new research, amlexanox has become a candidate for clinical evaluation in the treatment of obesity and related disorders, including diabetes. The study was conducted by researchers with the Life Sciences Institute at the University ... Read More

‘Lifestyle intervention’ for weight loss does not improve heart attack risk in diabetics

Longtime type 2 diabetics who undergo “lifestyle intervention” and lose weight do not reduce their heart attack and stroke risk, suggests a new study supported by the National Institutes of Health. The study focused on whether an intensive diet and exercise program resulting in weight loss would reduce the rates of heart disease, stroke, and cardiovascular-related deaths in overweight and obese people with type 2 diabetes. This demographic is already at greater risk for these conditions. For the study, researchers worked with more than 5,000 people. Half of the participants engaged in an intensive diet and exercise program while the ... Read More

Qsymia makers worry generics may take bite out of profits

Makers of the new obesity drug Qsymia have significantly scaled back their profit expectations after concerns that doctors may prescribe the drug’s ingredients separately rather than the drug itself. Vivus Inc., had estimated profits of as much as $3.6 billion per year, but scaled back its estimate to $1.2 billion, causing Vivus shares to tumble 7.7 percent earlier this week. Qsymia was one of two new long-term diet drugs approved by the Food and Drug Administration (FDA) earlier this year, making the drugs the first weight loss medications to be approved in 13 years. Qsymia was thought to be the ... Read More