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Zoloft 120 articles

New screening for newborns could detect heart defects faster

The British Heart Foundation is calling for a quick and inexpensive test to be performed on all newborns to help detect potentially life threatening heart defects. The pulse oximeter is a device that clips onto the fingertip and measures the oxygen levels in the blood. Oximeters have been used in hospitals for more than 20 years. In the United States, the oximeter test is used on newborns in select states. Researchers have found that when the test is used on newborns it can identify 75 percent of the most serious cardiac abnormalities. When used with traditional methods, 92 percent of ... Read More

Widely used SSRIs raise concerns of birth defects

According to a recent study, nearly 75 percent of all antidepressants were prescribed to patients without documented psychiatric conditions by non-psychiatrists in 2007, raising a host of concerns including the potential for patients to suffer serious side effects from the drugs that could put their unborn children at risk. The study, which was published in the Health Affairs journal, was co-authored by Mark Olfson, a professor of clinical psychiatry at Columbia University. The results were reported by the Wall Street Journal. Antidepressants were the second-most widely prescribed class of drugs in 2010, second only to cholesterol-lowering statins. Zoloft or a ... Read More

Antipsychotic fails to help veterans with chronic PTSD

Risperdal, an antipsychotic drug commonly prescribed to veterans with posttraumatic stress disorder (PTSD) when antidepressants fail to work, does not help numb the symptoms of the PTSD, according to a study published last week in the Journal of the American Medical Association. Only two antidepressant medications, Zoloft and Paxil, are approved by the Food and Drug Administration (FDA) to treat PTSD, though neither drug has been shown to be effective at treating those with a chronic form of the condition. With few FDA-approved options available, doctors have begun prescribing Risperdal to patients when antidepressants fail to alleviate their symptoms. Risperdal ... Read More

Millions awarded to women in Paxil, birth defects lawsuits

GlaxoSmithKline has awarded millions of dollars in compensation to women who took the antidepressant Paxil (paroxetine) while pregnant and delivered babies with serious birth defects. Paxil is a type of medication known as selective serotonin reuptake inhibitors (SSRIs), and is prescribed for the treatment of depression and anxiety disorder. Other brands of SSRIs include Zoloft, Lexapro, Prosac and Celexa. Paxil is considered more toxic to unborn babies than any other SSRI, and is listed as a Category D drug. All other SSRI drugs are Category C drugs, meaning they are safer for use during pregnancy. Since 2005, studies have linked ... Read More

Women should consider SSRI risks to fetuses

What a woman consumes when she is pregnant can have a detrimental effect on her unborn child. Because of this, the Food and Drug Administration (FDA) puts all prescription drugs into one of five categories based on harm to the fetus – A, B, C, D and X. These categories range from A, where there is no harm to the fetus in human studies, to X, where the medication should never be used in pregnant women because the risks to the fetus outweigh any benefit to the mother or fetus. All selective serotonin reuptake inhibitors, or SSRIs, except for paroxetine, ... Read More

Study: SSRI use during pregnancy increases risk of autism

Pregnant women who take a class of antidepressants may be putting their unborn children at risk for autism, a new study suggests. The antidepressants involved in the study are selective serotonin reuptake inhibitors (SSRIs) and include brands such as Paxil, Prozac, Celexa and Zoloft. Autism is a developmental disorder that appears in the first three years of life, and affects the brain’s normal development of social and communication skills. The incidence of autism has increased dramatically over the past 30 years, from 4 in 10,000 children to 40 in 10,000. SSRIs are used to treat depression, anxiety disorder, and some ... Read More

Most pregnant women taking medication despite possible risks

Eighty percent of pregnant women in America use at least one prescription or over-the-counter medication even though the safety of those drugs on fetuses is not always guaranteed, according to data from two long-running studies. Half of pregnant women said they used a medication during the first trimester of pregnancy, when the fetus is developing. In comparison, 30 years ago, only 30 percent of women used over-the-counter or prescription drugs during the first trimester of pregnancy. What concerns doctors is that many of these medications have never been studied in pregnant women to determine if use during pregnancy increases birth ... Read More

GSK avoided questions about safety of Paxil during pregnancy

In 2001, Beverly* wrote an e-mail to the drug maker GlaxoSmithKline (GSK). For four years she had taken the company’s antidepressant to treat panic attacks. She called it a miracle drug. But her e-mail to GSK expressed deep concern. Beverly had recently married and started actively trying to get pregnant. At the time she had written GSK, she had already lost one pregnancy when, at six months gestation, a rare but serious heart defect was detected and tests showed the baby would likely not survive to term or survive the necessary open heart surgery to save his life if he ... Read More

Tamoxifen with antidepressants may raise risk of breast cancer recurrence

The Food and Drug Administration (FDA) is expected to issue a warming to doctors about an increased risk of the recurrence of breast cancer with patients taking both the breast cancer drug tamoxifen and select antidepressants, according to a study released last week at the American Society of Clinical Oncology’s annual meeting. Researchers at Medco Health Solutions Inc. studied an estimated 1,300 women and found that women who were taking antidepressants such as Paxil, Prozac or Zoloft along with tamoxifen for at least one year had a breast-cancer recurrence rate of 16 percent. Women who were not taking the drugs ... Read More

FDA issues warning of serious adverse reaction to antidepressants

Several popular medications prescribed to treat depression, including Effexor, Paxil, and Prozac, have issued changes to the “Contradictions and Warnings” sections of their labels to warn of a potentially life-threatening adverse reaction known as Neuroleptic Malignant Syndrome (NMS). NMS is a neurological disorder that presents with muscle rigidity, fever, autonomic instability and cognitive changes such as delirium and associated with elevated levels of the enzyme creatine phosphokinase. Once symptoms appear, the progression of the condition is rapid, reaching peak intensity in as little as three days. Symptoms can last anywhere from eight hours to 40 days. The symptoms of NMS ... Read More