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Zoloft 120 articles

Few resources give reliable information about safety of medication during pregnancy

Women have few reliable and easy-to-understand resources available to tell them what medications may be harmful to their unborn child if the drugs are used during pregnancy, the Centers for Disease Control and Prevention (CDC) has found. Women usually search the internet for information about pregnancy in general. However, when CDC researchers examined 25 pregnancy-related websites they found contradictory information about which drugs pose risks to pregnant women or their fetuses. One site listed 22 products as safe that were considered risky on another site. Plus, there was no information to back up safety claims made for 40 percent of ... Read More

SSRIs may not increase stillbirth, infant death, but still carry birth defect risk

The most widely prescribed class of antidepressants, if taken during pregnancy, do not increase the risk of stillbirth or newborn death, a new study suggests. However, several studies have shown that the drugs can cause birth defects, premature birth, and other problems. The lastest study was published in the Journal of the American Medical Association (JAMA) and involved data from prescription registries, patient registries, and birth registries from Denmark, Finland, Iceland, Norway, and Sweden. Data from more than 1.6 million women included about 30,000 pregnant women who had filled a prescription for antidepressants known as selective serotonin reuptake inhibitors, or ... Read More

Woman files lawsuit alleging Zoloft is ineffective

A woman is suing Pfizer alleging the drug company withheld information that its antidepressant Zoloft was no more effective than placebo, and she wants Pfizer to reimburse her and other patients who were fooled into buying the drug over the course of years. Zoloft is in a class of antidepressants known as selective selective serotonin reuptake inhibitors (SSRI), which also includes the brand names Paxil, Celexa, Lexapro and Prozac. The plaintiff says she took Zoloft from 2005 through 2008, during which her doctor kept increasing her dosage. She said the medication did not improve her symptoms of depression; however, her ... Read More

New drug reaction warnings placed on SSRI and SNRI antidepressants

Patients who use some types of antidepressants with other serotonergic drugs are at an increased risk for developing a potentially life threatening drug reaction known as serotonin syndrome. The drug labels for several antidepressants in the selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) classes now contain a new warning that the drugs should not be used with other serotonergic drugs (including Triptans, Tricyclic antidepressants, Fentanyl, Lithium, Tramadol, Tryptonphan, Buspirone, and St. John’s Wort) and with drugs that impair metabolism of serotonin (in particular, MAOIs, both those intended to treat psychiatric disorders and also others, such as Linezolid and ... Read More

SSRIs increase risk of birth defects but not stillbirth or infant death

Taking antidepressants during pregnancy does not increase the chances that the baby will die in utero or shortly after birth, a new study suggests. However, using the medication while pregnant does increase the likelihood that babies will be born with birth defects. The study is based on a class of antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, which include the brand-name drugs Zoloft, Paxil, Lexapro and Prozac. Researchers studied 1.6 million women who delivered singletons in Nordic countries from 1996 to 2007. Before accounting for risks that can potentially lead to stillbirth or infant death, researchers noticed a ... Read More

Canadian judge certifies class action lawsuit against Paxil

It was devastating for Faith Gibson of British Columbia to learn that her daughter Meah Bartram was born with a hole in her heart. But it was even more crushing for Gibson to learn two weeks later that her daughter’s birth defect could have been prevented. Two weeks after she delivered Meah, drug maker GlaxoSmithKline (GSK) warned doctors that taking the antidepressant Paxil during pregnancy could increase the risk of cardiovascular defects. Faith used Paxil during her pregnancy and based on information available to her at the time, she believed the drug to be safe for her unborn child. When ... Read More

50th anniversary for Kefauver-Harris Amendment to ensure safer, more effective drugs

This year marks the 50th anniversary of the Kefauver-Harris Amendment, action that required drug companies provide more thorough data on the safety and efficacy of prescription drugs before they are approved. The amendment led to the development of evidence-based drug evaluations carried out by the Food and Drug Administration (FDA). Despite these efforts, some drug companies still try to withhold information on adverse drug reactions in order to bolster their own profits. Much of the credit for the passage of the Kefauver-Harris Amendment goes to Frances O’Kelsey. More than 50 years ago, when O’Kelsey was first hired to serve as ... Read More

Lexapro may be effective in treating symptoms of menopause

The antidepressant escitalopram, known by the brand name Lexapro, was effective in decreasing hot flash frequency and severity in menopausal women, according to a small clinical trial. Lexapro is in a class of medications known as selective serotonin reuptake inhibitors (SSRIs). It is approved to treat depression and generalized anxiety disorder, and excessive worry and tension that lasts for 6 months or longer. Other brand-name antidepressants in the SSRI class include Paxil, Zoloft, Celexa, and Prozac. The study was conduced in 2009 and has not resulted in the drug’s maker seeking approval for the new indication. However, some doctors prescribe ... Read More

Systematic review of studies finds numerous problems with SSRI use during pregnancy

Women who took antidepressants while pregnant were more likely to miscarry, deliver prematurely, and to give birth to babies with developmental and health problems, according to a new systematic review of studies. The review focused on selective serotonin reuptake inhibitors (SSRIs), the most commonly prescribed antidepressants in the United States. Brand names include Paxil, Zoloft, Celexa, Lexapro and Prozac. Researchers from Beth Israel Deaconess Medical Center in Waltham, Mass., noted that women who took SSRIs while pregnant were more likely to deliver their babies preterm. They were also more likely to develop high blood pressure that can lead to pre-eclampsia, ... Read More

Studies reveal risks, help women make informed decisions about taking SSRIs during pregnancy

Janice Price, 37, is waiting for answers. The 37-year-old woman has wanted to start a family with her husband for at least two years. But she is taking an antidepressant and worries about studies that have linked antidepressant use during pregnancy to problems for both the expectant mother and her unborn child. Recent studies have shown that pregnant women who take a common type of antidepressant known as selective serotonin reuptake inhibitors (SSRIs) have an increased risk of developing high blood pressure that can lead to pre-eclampsia, a condition that can be life threatening to both mother and the fetus. ... Read More